Evidence map›Paper›PMID 38567509›Full record

ArticleHypertension (Dallas, Tex. : 1979)2024

Maintenance of Normal Blood Pressure From Middle to Older Age: Results From the Atherosclerosis Risk in Communities Study.

Kathryn Foti, Josef Coresh, Paul K Whelton, Kunihiro Matsushita, Shakia T Hardy, Kristi Reynolds, C Barrett Bowling, Keenan A Walker, Anna Kucharska-Newton, B Gwen Windham and 3 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Cellular and molecular mechanisms underlying cardiovascular aging.Cellular & molecular biology letters · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Kathryn FotiDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL (K.F., P.M.).ORCID 0000-0002-6380-2735
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (J.C., K.M.).ORCID 0000-0002-4598-0669
Paul K WheltonDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (P.K.W.).ORCID 0000-0002-2225-383X
Kunihiro MatsushitaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (J.C., K.M.).ORCID 0000-0002-7179-718X
Shakia T HardyGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chappel Hill, NC (S.T.H., A.K.-N.).ORCID 0000-0001-9211-0474
Kristi ReynoldsDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA (K.R.).ORCID 0000-0001-7619-1649
C Barrett BowlingDepartment of Veterans Affairs, Durham Geriatrics Research Education and Clinical Center, Durham, NC (C.B.B.).ORCID 0000-0001-6265-8623
Keenan A WalkerLaboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD (K.A.W.).ORCID 0000-0002-5989-9853
Anna Kucharska-NewtonGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chappel Hill, NC (S.T.H., A.K.-N.).ORCID 0000-0001-9864-467X
B Gwen WindhamDepartment of Medicine, Division of Geriatrics, University of Mississippi Medical Center, Jackson, MS (B.G.W., M.G.).ORCID 0000-0001-6240-5044
Michael GriswoldDepartment of Medicine, Division of Geriatrics, University of Mississippi Medical Center, Jackson, MS (B.G.W., M.G.).ORCID 0000-0001-8106-5516
Joseph E SchwartzDepartment of Medicine, Columbia University Irving Medical Center, New York, NY (J.E.S.).ORCID 0000-0002-8944-3566
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL (K.F., P.M.).ORCID 0000-0002-4711-5492
Alabama Department of Public Health · USJohns Hopkins University · USUniversity of Mississippi Medical Center · USUniversity of North Carolina at Chapel Hill · USColumbia University Irving Medical Center · USDuke University · USKaiser Permanente · USNational Institute on Aging · USTulane University · US

Funding

ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - COORDINATING CENTER - TASK AREA B.2 AND B.375N92022D00001 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID · 2022 to 2025
$13.7M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2 of 5U01HL096917 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI MOSLEY, THOMAS H · 2010 to 2018
$11.9M
ARIC Neurocognitive Study (ARIC-NCS) Renewal UNC 4 of 5U01HL096899 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J · 2010 to 2018
$7.5M
ARIC Neurocognitive Study (ARIC-NCS)U01HL096902 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2010 to 2018
$7.4M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 4 of 5U01HL096814 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUGHES, TIMOTHY M., WAGENKNECHT, LYNNE E · 2010 to 2018
$6.5M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00003 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2022 to 2025
$5.1M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00005 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WAGENKNECHT, LYNNE E · 2022 to 2025
$5.0M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00004 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI WINDHAM, BEVERLY GWEN · 2022 to 2025
$4.8M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00002 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF · 2022 to 2025
$4.7M
Understanding immune/inflammatory and vascular mechanisms in brain aging and Alzheimer's diseaseZIAAG000348 · NIA · NATIONAL INSTITUTE ON AGING · PI WALKER, KEENAN · 2021 to 2025
$2.8M
Peer Support for Lowering Blood Pressure among Adolescents: A Pilot, Randomized Controlled TrialK01HL164763 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Shakia Tranece Hardy · 2022 to 2026
$729k
NHLBI NIH HHS 75N92022D00001NHLBI NIH HHS 75N92022D00002NHLBI NIH HHS 75N92022D00003NHLBI NIH HHS 75N92022D00004NHLBI NIH HHS 75N92022D00005NHLBI NIH HHS K01 HL164763NHLBI NIH HHS U01 HL096812NHLBI NIH HHS U01 HL096814NHLBI NIH HHS U01 HL096899NHLBI NIH HHS U01 HL096902NHLBI NIH HHS U01 HL096917
6 · The paper itself

Abstract

backgroundIt is unknown whether maintaining normal blood pressure (BP) from middle to older age is associated with improved health outcomes.

methodsWe estimated the proportion of Atherosclerosis Risk in Communities study participants who maintained normal BP from 1987 to 1989 (visit 1) through 1996 to 1998 and 2011 to 2013 (over 4 and 5 visits, respectively). Normal BP was defined as systolic BP <120 mm Hg and diastolic BP <80 mm Hg, without antihypertensive medication. We estimated the risk of cardiovascular disease, dementia, and poor physical functioning after visit 5. In exploratory analyses, we examined participant characteristics associated with maintaining normal BP.

resultsAmong 2699 participants with normal BP at baseline (mean age 51.3 years), 47.1% and 15.0% maintained normal BP through visits 4 and 5, respectively. The hazard ratios comparing participants who maintained normal BP through visit 4 but not visit 5 and through visit 5 versus those who did not maintain normal BP through visit 4 were 0.80 (95% CI, 0.63-1.03) and 0.60 (95% CI, 0.42-0.86), respectively, for cardiovascular disease, and 0.85 (95% CI, 0.71-1.01) and 0.69 (95% CI, 0.54-0.90), respectively, for poor physical functioning. Maintaining normal BP through visit 5 was more common among participants with normal body mass index versus obesity at visit 1, those with normal body mass index at visits 1 and 5, and those with overweight at visit 1 and overweight or normal body mass index at visit 5, compared with those with obesity at visits 1 and 5.

conclusionsMaintaining normal BP was associated with a lower risk of cardiovascular disease and poor physical functioning.

Indexed as

AtherosclerosisBlood PressureAgedAge FactorsBlood Pressure DeterminationCardiovascular DiseasesDementiaFemaleHumansHypertensionMaleMiddle AgedRisk AssessmentRisk FactorsUnited Statesagingblood pressurebody mass indexcardiovascular diseasesobesity

Identifiers

PMID38567509
PMCPMC11096029
OpenAlexW4393858894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.