Evidence map›Paper›PMID 38567481›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Incidence of Influenza-related Medical Encounters and the Associated Healthcare Resource Use and Complications Across Adult Age Groups in the United States During the 2015-2020 Influenza Seasons.

Ian McGovern, Katherine Cappell, Alina N Bogdanov, Mendel D M Haag

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ian McGovernCSL Seqirus, Center for Outcomes Research and Epidemiology, Waltham, Massachusetts, USA.ORCID 0000-0002-0282-7728
Katherine CappellVeradigm, Real World Evidence, Chicago, Illinois, USA.
Alina N BogdanovVeradigm, Real World Evidence, Chicago, Illinois, USA.
Mendel D M HaagCSL Seqirus, Center for Outcomes Research and Epidemiology, Amsterdam, The Netherlands.ORCID 0000-0001-7895-7556
Diagnostics for the Real World (United States) · USSeqirus (United States) · US

Funding

CSL Seqirus
6 · The paper itself

Abstract

backgroundResearch on influenza burden in adults has focused on crude subgroups with cut-points at 65 years, limiting insight into how burden varies with increasing age. This study describes the incidence of influenza-related outpatient visits, emergency room visits, and hospitalizations, along with healthcare resource use and complications in the aging adult population.

methodsIndividuals aged ≥18 years in the United States were evaluated retrospectively in 5 seasonal cohorts (2015-2020 seasons) in strata of age with 5-year increments. Person-level electronic medical records linked to pharmacy and medical claims were used to ascertain patient characteristics and outcomes. Influenza-related medical encounters were identified based on diagnostic codes (International Classification of Diseases, 10th Edition, codes J09*-J11*).

resultsIncidence of influenza-related outpatient visits was highest among people aged 18-34 years and declined with increasing age. For emergency room visits, incidence tended to be elevated for people aged 18-34 years, relatively stable from 35 through 60, and increased rapidly after age 60 years. Hospitalization incidence remained relatively stable until about 50 years of age and then increased with age. One in 3 patients was diagnosed with pneumonia after hospitalization, regardless of age. Across seasons, age groups, and clinical settings, on average, 40.8% of individuals were prescribed antivirals and 17.2% antibiotics.

conclusionsIncidence of influenza-related hospitalizations begins to increase around age 50 years rather than the more common cut-point of 65, whereas incidence of outpatient visits was highest among younger adults. Influenza infections frequently led to antiviral and antibiotic prescriptions, underscoring the role influenza vaccination can play in combating antimicrobial resistance.

Indexed as

HospitalizationInfluenza, HumanSeasonsAdolescentAdultAgedAged, 80 and overAge FactorsEmergency Service, HospitalFemaleHealth ResourcesHumansIncidenceMaleMiddle AgedRetrospective StudiesAntibioticsAntiviralsDisease BurdenIncidenceInfluenza

Identifiers

PMID38567481
PMCPMC11426264
OpenAlexW4393902549

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.