ReviewBone reports2024
The multi-faceted nature of age-associated osteoporosis.
Review in Bone reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed.
- Micronutrients and omega-3 PUFAs to promote healthy ageing: informing a physiology-based complementation strategy.GeroScience · 2026Review
- Fragility fracture risk prediction using quantitative magnetic resonance and Vertebral Bone Quality scoring beyond density.World journal of methodology · 2026Review
- Angiogenic and Osteogenic Strategies for Skeletal Regeneration in Aging.Current osteoporosis reports · 2026Review
- Bioactive Phytochemicals fromNutrients · 2026Article
- Moth-Eaten Osteolysis of Multiple Foot Bones After a Conservatively Treated "Stable" Ankle Fracture: A Case Report and Literature Review.Clinical case reports · 2026Article
- Weight-bearing exercise intensity and physiotherapy outcomes in older Nigerian women with osteoporosis: a multicenter a cross-sectional study.Archives of osteoporosis · 2026Article
- Mesenchymal Stem/Stromal Cells-Derived Exosomal Micro-RNA Delivery Enhances Bone Repair in Osteoporotic Conditions.Tissue engineering. Part A · 2026Article
- Trends and Epidemiology of Fall-Related Hospitalizations Among Older Adults in the Split-Dalmatia County, Croatia: A Retrospective Descriptive Study from 2020 to 2024.Medicina (Kaunas, Lithuania) · 2026Article
- The SINTER study: a recall-by-genotype design with multidimensional musculoskeletal phenotyping across internal-medicine outpatient clinics.European journal of epidemiology · 2026Article
- Korean Medicine for Aging Cohort (KoMAC) study-a prospective multicentre cohort in urban and rural Korea: cohort profile.BMJ open · 2026Article
- Geroprotective interventions preserve trabecular bone during ageing in female mice.bioRxiv : the preprint server for biology · 2026Article
- BodyMAE: A Surface-Area Aware Masked Autoencoder for Body Composition Estimation from 3D Body Scans.medRxiv : the preprint server for health sciences · 2026Article
- Impact of sleep duration on bone mineral density and osteoporosis risk: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Review
- The Effect of Stress Urinary Incontinence on Kinesiophobia in Postmenopausal Women with Osteoporosis: A Cross-Sectional Study.BMC women's health · 2026Article
- Polypharmacy and Bone Health in Patients with Type 2 Diabetes Mellitus: A Narrative Review.Journal of bone metabolism · 2026Article
- FRAX-based national survey of osteoporotic fracture risk, related knowledge, and associated factors, among Egyptian adults aged 40 years and older, 2025.Scientific reports · 2026Article
- Long-term enoxaparin use and osteoporosis risk: a real-world cohort study with integrative computational and network toxicology approaches.Journal of translational medicine · 2026Article
- Acid-Base Dysregulation Links Aging Metabolism to Frailty.Aging cell · 2026Article
- Degradable piezoelectric KNN/PLLA nanofibers for promoting osteogenesis and angiogenesis in bone regeneration.Biomedical engineering online · 2026Article
- Machine learning model integrating oral microbiota and clinical features for predicting osteoporosis and bone loss in high-altitude populations.BMC microbiology · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Age-associated osteoporosis (AAOP) poses a significant health burden, characterized by increased fracture risk due to declining bone mass and strength. Effective prevention and early treatment strategies are crucial to mitigate the disease burden and the associated healthcare costs. Current therapeutic approaches effectively target the individual contributing factors to AAOP. Nonetheless, the management of AAOP is complicated by the multitude of variables that affect its development. Main intrinsic and extrinsic factors contributing to AAOP risk are reviewed here, including mechanical unloading, nutrient deficiency, hormonal disbalance, disrupted metabolism, cognitive decline, inflammation and circadian disruption. Furthermore, it is discussed how these can be targeted for prevention and treatment. Although valuable as individual targets for intervention, the interconnectedness of these risk factors result in a unique etiology for every patient. Acknowledgement of the multifaceted nature of AAOP will enable the development of more effective and sustainable management strategies, based on a holistic, patient-centered approach.
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