Evidence map›Paper›PMID 38566007›Full record

ArticleBMC gastroenterology2024

Impact of severe postoperative complications on the prognosis of older patients with colorectal cancer: a two-center retrospective study.

Daiki Matsubara, Koji Soga, Jun Ikeda, Tatsuya Kumano, Masato Mitsuda, Tomoki Konishi, Shuhei Komatsu, Katsumi Shimomura, Fumihiro Taniguchi, Yasuhiro Shioaki and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Daiki MatsubaraDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Koji SogaDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan. soga@koto.kpu-m.ac.jp.
Jun IkedaDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Tatsuya KumanoDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Masato MitsudaDepartment of Surgery, Japanese Red Cross Maizuru Hospital, 427, Kuratani, Maizuru, 624-0906, Kyoto, Japan.
Tomoki KonishiDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Shuhei KomatsuDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Katsumi ShimomuraDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Fumihiro TaniguchiDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Yasuhiro ShioakiDepartment of Gastroenterological Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749, Honmachi, Higashiyama-ku, 605-0981, Kyoto, Japan.
Eigo OtsujiDivision of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, 602-0841, Kyoto, Japan.
Kyoto first Red Cross hospital · JPMaizuru Municipal Hospital · JPKyoto Prefectural University of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe occurrence of postoperative complications may affect short-term outcomes and prognosis of patients with various malignancies. However, the prognostic impact of these complications in older patients with colorectal cancer (CRC) remains unclear. Therefore, this study aimed to investigate the impact of severe postoperative complications on the oncological outcomes of older (aged ≥ 80 years) and non-older (aged < 80 years) patients with CRC.

methodsWe retrospectively analyzed 760 patients with stage I-III CRC who underwent curative surgery in two institutions between 2013 and 2019. The patients were categorized into older (aged ≥ 80 years, 191 patients) and non-older (aged < 80 years, 569 patients) groups. Short- and long-term outcomes were compared between the two groups.

resultsThe incidence of severe postoperative complications did not differ between the two groups (p = 0.981). Cancer-specific survival (CSS) was significantly worse in older patients with severe complications than in those without severe complications (p = 0.007); meanwhile, CSS did not differ between the non-older patients with severe complications and those without severe complications. Survival analysis revealed that the occurrence of severe postoperative complications was an independent prognostic factor for CSS in older patients (hazard ratio = 4.00, 95% confidence interval: 1.27-12.6, p = 0.017).

conclusionCRC surgery can be safely performed in older and non-older patients. Moreover, the occurrence of severe postoperative complications might more strongly affect the prognosis of older patients than that of non-older patients.

Indexed as

Colorectal NeoplasmsPostoperative ComplicationsAgedHumansPrognosisRetrospective StudiesRisk FactorsSurvival RateColorectal cancerMinimally invasive surgeryOlder patientsSevere postoperative complication

Identifiers

PMID38566007
PMCPMC10988919
OpenAlexW4393427383

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.