Evidence map›Paper›PMID 38565971›Full record

ArticleNature biotechnology2025

Self-pigmenting textiles grown from cellulose-producing bacteria with engineered tyrosinase expression.

Kenneth T Walker, Ivy S Li, Jennifer Keane, Vivianne J Goosens, Wenzhe Song, Koon-Yang Lee, Tom Ellis

Open access · hybridAbstract read
In one paragraph

Article in Nature biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 57 citations in OpenAlex.

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  7. Engineering an Optogenetic pH-Modulator in Bacteria.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kenneth T WalkerImperial College Centre for Synthetic Biology, Imperial College London, London, UK.
Ivy S LiImperial College Centre for Synthetic Biology, Imperial College London, London, UK.ORCID http://orcid.org/0009-0008-0941-1988
Jennifer KeaneModern Synthesis, London, UK.
Vivianne J GoosensImperial College Centre for Synthetic Biology, Imperial College London, London, UK.
Wenzhe SongDepartment of Aeronautics, Imperial College London, London, UK.
Koon-Yang LeeDepartment of Aeronautics, Imperial College London, London, UK.
Tom EllisImperial College Centre for Synthetic Biology, Imperial College London, London, UK. t.ellis@imperial.ac.uk.ORCID http://orcid.org/0000-0001-5392-976X
Imperial College London · GB

Funding

RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/S507994/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/M002306/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/N026489/1
6 · The paper itself

Abstract

Environmental concerns are driving interest in postpetroleum synthetic textiles produced from microbial and fungal sources. Bacterial cellulose (BC) is a promising sustainable leather alternative, on account of its material properties, low infrastructure needs and biodegradability. However, for alternative textiles like BC to be fully sustainable, alternative ways to dye textiles need to be developed alongside alternative production methods. To address this, we genetically engineer Komagataeibacter rhaeticus to create a bacterial strain that grows self-pigmenting BC. Melanin biosynthesis in the bacteria from recombinant tyrosinase expression achieves dark black coloration robust to material use. Melanated BC production can be scaled up for the construction of prototype fashion products, and we illustrate the potential of combining engineered self-pigmentation with tools from synthetic biology, through the optogenetic patterning of gene expression in cellulose-producing bacteria. With this study, we demonstrate that combining genetic engineering with current and future methods of textile biofabrication has the potential to create a new class of textiles.

Indexed as

CelluloseMonophenol MonooxygenaseTextilesBacteriaGenetic EngineeringMelaninsCelluloseMelaninsMonophenol Monooxygenase

Identifiers

PMID38565971
PMCPMC11919691
OpenAlexW4393397039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.