Evidence map›Paper›PMID 38565882›Full record

ArticleScientific reports2024

Comprehensive landscape of neutralizing antibody and cell-mediated response elicited by the 1/5 fractional dose of 17DD-YF primary vaccination in adults.

Laise Rodrigues Reis, Ismael Artur Costa-Rocha, Thais Abdala-Torres, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Márcio Sobreira Silva Araújo, Elaine Spezialli, Lis Ribeiro do Valle Antonelli, Rosiane Aparecida da Silva-Pereira, Gregório Guilherme Almeida and 19 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. T Cell Responses During Dengue Infection.Current topics in microbiology and immunology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 10 institutions in 2 countries.

Laise Rodrigues ReisInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Ismael Artur Costa-RochaInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Thais Abdala-TorresInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Ana Carolina Campi-AzevedoInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Vanessa Peruhype-MagalhãesInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Márcio Sobreira Silva AraújoInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Elaine SpezialliInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Lis Ribeiro do Valle AntonelliInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Rosiane Aparecida da Silva-PereiraInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Gregório Guilherme AlmeidaInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Eder Gatti FernandesInstituto de Infectologia Emílio Ribas, São Paulo, SP, Brazil.
Francieli Fontana Sutile Tardetti FantinatoDepartamento de Vigilância das Doenças Transmissíveis, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, DF, Brazil.
Carla Magda Allan Santos Domingues *External Consultant, Independent Researcher, Brasília, DF, Brazil.
Maria Cristina Ferreira LemosSecretaria de Estado de Saúde, Rio de Janeiro, RJ, Brazil.
Alexandre ChieppeSuperintendência de Vigilância em Saúde, Secretaria Municipal de Saúde do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Jandira Aparecida Campos LemosSecretaria Municipal de Saúde de Belo Horizonte, Belo Horizonte, MG, Brazil.
Jordana Grazziela Coelho-Dos-ReisLaboratório de Virologia Básica e Aplicada, Instituto de Ciências Biológicas da Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brazil.
Sheila Maria Barbosa de LimaDepartamento de Desenvolvimento Experimental e Pré-Clínico, Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos - FIOCRUZ, Rio de Janeiro, RJ, Brazil.
Adriana de Souza AzevedoLaboratório de Análise Imunomolecular, Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos - FIOCRUZ, Rio de Janeiro, RJ, Brazil.
Waleska Dias SchwarczLaboratório de Análise Imunomolecular, Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos - FIOCRUZ, Rio de Janeiro, RJ, Brazil.
Luiz Antônio Bastos CamachoEscola Nacional de Saúde Pública - FIOCRUZ, Rio de Janeiro, RJ, Brazil.
Maria de Lourdes de Sousa MaiaAssessoria Clínica, Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos - FIOCRUZ, Rio de Janeiro, RJ, Brazil.
Tatiana Guimarães de NoronhaAssessoria Clínica, Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos - FIOCRUZ, Rio de Janeiro, RJ, Brazil.
Caroline DuaultHuman Immune Monitoring Center, Stanford University, Stanford, CA, USA.
Yael Rosenberg-HassonHuman Immune Monitoring Center, Stanford University, Stanford, CA, USA.
Andréa Teixeira-CarvalhoInstituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil.
Holden Terry Maecker *Human Immune Monitoring Center, Stanford University, Stanford, CA, USA. maecker@stanford.edu.
Olindo Assis Martins-Filho *Instituto René Rachou, Fundação Oswaldo Cruz - FIOCRUZ-Minas, Belo Horizonte, MG, Brazil. olindo.filho@fiocruz.br.
Collaborative Group for Studies of Yellow Fever Vaccine
Fundação Oswaldo Cruz · BRInstituto de Tecnologia e Pesquisa · BRSecretaria Municipal de Saúde · BRStanford University · USUniversidade Federal de Minas Gerais · BREscola Nacional de Saúde Pública · BRInstituto de Infectologia Emílio Ribas · BRMinistério da Saúde · BRSecretaria da Saúde · BRStanford Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed at evaluating the YF-specific neutralizing antibody profile besides a multiparametric analysis of phenotypic/functional features of cell-mediated response elicited by the 1/5 fractional dose of 17DD-YF vaccine, administered as a single subcutaneous injection. The immunological parameters of each volunteer was monitored at two time points, referred as: before (Day 0) [Non-Vaccinated, NV

Indexed as

Yellow FeverYellow Fever VaccineAdultAntibodies, NeutralizingAntibodies, ViralCD8-Positive T-LymphocytesHumansInterleukin-10Tumor Necrosis Factor-alphaVaccinationAntibodies, NeutralizingAntibodies, ViralInterleukin-10Tumor Necrosis Factor-alphaYellow Fever Vaccine17DD vaccineAdultsCellular memoryFractional doseNeutralizing antibodiesYellow fever

Identifiers

PMID38565882
PMCPMC10987530
OpenAlexW4393442644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.