Evidence map›Paper›PMID 38564664›Full record

ArticlemBio2024

Promoter regulatory mode evolution enhances the high multidrug resistance of

Chengzhen Wang, Jun Yang, Zeling Xu, Luchao Lv, Sheng Chen, Mei Hong, Jian-Hua Liu

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Emergence ofVirulence · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Multiple Copies of Tigecycline Gene ClusterAntibiotics (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Emergence of Mobilized Tigecycline Resistance Gene ClusterTransboundary and emerging diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chengzhen WangState Key Laboratory for Animal Disease Control and Prevention, Guangdong Laboratory for Lingnan Modern Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Jun YangState Key Laboratory for Animal Disease Control and Prevention, Guangdong Laboratory for Lingnan Modern Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-2543-1275
Zeling XuGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou, China.ORCID 0000-0003-4662-8111
Luchao LvState Key Laboratory for Animal Disease Control and Prevention, Guangdong Laboratory for Lingnan Modern Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0003-4978-841X
Sheng ChenState Key Lab of Chemical Biology and Drug Discovery and the Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.ORCID 0000-0003-3526-7808
Mei HongCollege of Life Sciences, South China Agricultural University, Guangzhou, China.
Jian-Hua LiuState Key Laboratory for Animal Disease Control and Prevention, Guangdong Laboratory for Lingnan Modern Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-3930-7857
South China Agricultural University · CNHong Kong Polytechnic University · HK

Funding

MOST | National Key Research and Development Program of China (NKPs) 2022YFC2303900the Guangdong Major Project of Basic and Applied Basic Research 2020B0301030007the Gurangdong Special Support Program Innovation Team 2019BT02N054the International Training Program for Outstanding Young Scientists in Universities in Guangdong Province HT202301811-02the Laboratory of Lingnan Modern Agriculture Project NT2021006
6 · The paper itself

Abstract

Antibiotic resistance could rapidly emerge from acquiring the mobile antibiotic resistance genes, which are commonly evolved from an intrinsic gene. The emergence of the plasmid-borne mobilized efflux pump gene cluster

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialEvolution, MolecularPromoter Regions, GeneticBacterial ProteinsEscherichia coliGene Expression Regulation, BacterialMembrane Transport ProteinsMultigene FamilyOperonTigecyclineAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsTigecyclineantibiotic resistanceevolutiongene regulationtigecyclinetmexCD-toprJ

Identifiers

PMID38564664
PMCPMC11077950
OpenAlexW4393404731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.