Evidence map›Paper›PMID 38564635›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Transcription factor C/EBPα is required for the development of Ly6C

Sunkyung Kim, Jing Chen, Feiya Ou, Tian-Tian Liu, Suin Jo, William E Gillanders, Theresa L Murphy, Kenneth M Murphy

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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  14. C/EBPα activatesScience immunology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sunkyung KimDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.
Jing ChenDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.
Feiya OuDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.
Tian-Tian LiuDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.ORCID 0000-0001-9377-9938
Suin JoDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.
William E GillandersDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.
Theresa L MurphyDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.
Washington University in St. Louis · US

Funding

Molecular Basis of cDC1 DevelopmentR01AI162643 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2025
$2.8M
Function of Wdfy4 in cross-presentation and immunityR01AI150297 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2019 to 2023
$2.5M
Understanding the Mechanisms of DC Licensing in CD8 T Cell PrimingR01CA248919 · NCI · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2021 to 2025
$2.3M
Function of Wdfy4 in cross-presentation and immunityR37AI150297 · NIAID · WASHINGTON UNIVERSITY · PI Kenneth M Murphy · 2025 to 2026
$1.1M
Mechanism of c-MYC repression by IRF8 in myeloid lineagesR21AI164142 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2021 to 2022
$433k
Transcriptional basis of embryonic macrophage developmentR21AI163421 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2023
$430k
The role of EMT transcription factor Zeb2 in fetal hematopoiesisF30HL167565 · NHLBI · WASHINGTON UNIVERSITY · PI CHEN, JING · 2023 to 2025
$142k
NCI NIH HHS R01 CA248919NHLBI NIH HHS F30 HL167565NIAID NIH HHS R01 AI150297NIAID NIH HHS R01 AI162643NIAID NIH HHS R21 AI163421NIAID NIH HHS R21 AI164142NIAID NIH HHS R37 AI150297
6 · The paper itself

Abstract

Monocytes comprise two major subsets, Ly6C

Indexed as

Gene Expression RegulationMonocytesAnimalsCCAAT-Enhancer-Binding ProteinsMiceMice, Inbred C57BLTranscription FactorsCCAAT-Enhancer-Binding ProteinsCEBPA protein, mouseTranscription FactorsC/EBPαclassical monocyteneutrophilnonclassical monocytetranscription factor

Identifiers

PMID38564635
PMCPMC11009651
OpenAlexW4393406332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.