Evidence map›Paper›PMID 38564631›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Polyphosphate affects cytoplasmic and chromosomal dynamics in nitrogen-starved

Sofia Magkiriadou, Willi L Stepp, Dianne K Newman, Suliana Manley, Lisa R Racki

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Polyphosphate synthesis is essential for phosphate and ATP homeostasis during nutrient upshift.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Micropipette aspiration reveals differential RNA-dependent viscoelasticity of nucleolar subcompartments.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Review
  8. Polyphosphate affects cytoplasmic and chromosomal dynamics in nitrogen-starvedProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Sofia MagkiriadouLaboratory of Experimental Biophysics, Institute of Physics, École Polytechnique Fédérale de Lausanne, Lausanne CH-1015, Switzerland.ORCID 0000-0001-7660-5012
Willi L SteppLaboratory of Experimental Biophysics, Institute of Physics, École Polytechnique Fédérale de Lausanne, Lausanne CH-1015, Switzerland.
Dianne K NewmanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Suliana ManleyLaboratory of Experimental Biophysics, Institute of Physics, École Polytechnique Fédérale de Lausanne, Lausanne CH-1015, Switzerland.ORCID 0000-0002-4755-4778
Lisa R RackiDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA 92037.ORCID 0000-0003-2209-7301
École Polytechnique Fédérale de Lausanne · CHCalifornia Institute of Technology · USScripps Research Institute · US

Funding

Using phage to interrogate bacterial heterochromatinDP2GM140918 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI RACKI, LISA R · 2020 to 2020
$2.7M
NIGMS NIH HHS DP2 GM140918Swiss National Science Foundation 182429
6 · The paper itself

Abstract

Polyphosphate (polyP) synthesis is a ubiquitous stress and starvation response in bacteria. In diverse species, mutants unable to make polyP have a wide variety of physiological defects, but the mechanisms by which this simple polyanion exerts its effects remain unclear. One possibility is that polyP's many functions stem from global effects on the biophysical properties of the cell. We characterize the effect of polyphosphate on cytoplasmic mobility under nitrogen-starvation conditions in the opportunistic pathogen

Indexed as

PolyphosphatesPseudomonas aeruginosaCytoplasmCytosolPolyphosphatescytoplasmic transportnucleoidpolyphosphatestarvation physiology

Identifiers

PMID38564631
PMCPMC11009631
OpenAlexW4393405624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.