ArticlePhysical and engineering sciences in medicine2024
On the accuracy of sequence methods for baroreflex sensitivity estimation.
Article in Physical and engineering sciences in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Decreased and Increased Baroreceptor Sensitivity Are Associated With Incident Heart Failure in the Elderly: A 15-Year Follow-Up Study.Clinical cardiology · 2026Article
- Spontaneous indices correlate with baroreflex gain only in adults with spinal cord injury.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- A secondary analysis of autonomic function during high-intensity interval exercise in adults with chronic stroke.Physiological reports · 2026Article
- Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit-stand maneuvers and spontaneous rest.Physiological reports · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In the absence of a true gold standard for non-invasive baroreflex sensitivity estimation, it is difficult to quantify the accuracy of the variety of techniques used. A popular family of methods, usually entitled 'sequence methods' involves the extraction of (apparently) correlated sequences from blood pressure and RR-interval data and the subsequent fitting of a regression line to the data. This paper discusses the accuracy of sequence methods from a system identification perspective, using both data generated from a known mathematical model and spontaneous baroreflex data. It is shown that sequence methods can introduce significant bias in the baroreflex sensitivity estimate, even when great care is taken in sequence selection.
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Registered trials
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