Evidence map›Paper›PMID 38564062›Full record

ArticleArchives of osteoporosis2024

The Dutch multidisciplinary guideline osteoporosis and fracture prevention, taking a local guideline to the international arena.

J P van den Bergh, P Geusens, N M Appelman-Dijkstra, H J G van den Broek, P J M Elders, G de Klerk, M van Oostwaard, H C Willems, M C Zillikens, W F Lems

Open access · hybridAbstract read
In one paragraph

Article in Archives of osteoporosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Effects of romosozumab on the peripheral and axial skeleton in postmenopausal women at high fracture risk: real-world evidence from DXA and HR-pQCT data.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Observational
  3. Beyond the Bone: Why Orthopaedics Matters in the Super-aged Era.Clinical orthopaedics and related research · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

J P van den BerghDepartment of Internal Medicine, VieCuri Medical Center, Venlo, the Netherlands. joop.vandenbergh@maastrichtuniversity.nl.
P GeusensDepartment of Internal Medicine, Subdivision Rheumatology, Maastricht University Medical Center, Maastricht, the Netherlands.
N M Appelman-DijkstraDepartment of Internal Medicine, Division Endocrinology, Leiden University Medical Center, Leiden, the Netherlands.
H J G van den BroekOsteoporose Vereniging, Bilthoven, the Netherlands.
P J M EldersDepartment of General Practice, Amsterdam Public Health Institute, Amsterdam UMC, Amsterdam, the Netherlands.
G de KlerkDepartment of Surgery, ADRZ, Goes, the Netherlands.
M van OostwaardDepartment of Internal Medicine, VieCuri Medical Center, Venlo, the Netherlands.
H C WillemsDepartment of Internal Medicine and Geriatrics, Amsterdam University Medical Center, Amsterdam, the Netherlands.
M C ZillikensDepartment of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
W F LemsDepartment of Rheumatology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Amsterdam University Medical Centers · NLMaastricht University · NLAdmiraal De Ruyter Ziekenhuis · NLErasmus MC · NLGGD Amsterdam · NLLeiden University Medical Center · NLVieCuri Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2018, a grant was provided for an evidence-based guideline on osteoporosis and fracture prevention based on 10 clinically relevant questions.

methodsA multidisciplinary working group was formed with delegates from Dutch scientific and professional societies, including representatives from the patient's organization and the Dutch Institute for Medical Knowledge. The purpose was to obtain a broad consensus among all participating societies to facilitate the implementation of the updated guideline.

resultsNovel recommendations in our guideline are as follows: - In patients with an indication for DXA of the lumbar spine and hips, there is also an indication for VFA. - Directly starting with anabolic drugs (teriparatide or romosozumab) in patients with a very high fracture risk; - Directly starting with zoledronic acid in patients 75 years and over with a hip fracture (independent of DXA); - Directly starting with parenteral drugs (denosumab, teriparatide, zoledronic acid) in glucocorticoid-induced osteoporosis with very high fracture risk; - A lifelong fracture risk management, including lifestyle, is indicated from the start of the first treatment.

conclusionIn our new multidisciplinary guideline osteoporosis and fracture prevention, we developed 5 "relatively new statements" that are all a crucial step forward in the optimization of diagnosis and treatment for fracture prevention. We also developed 5 flowcharts, and we suppose that this may be helpful for individual doctors and their patients in daily practice and may facilitate implementation.

Indexed as

Hip FracturesOsteoporosisEthnicityHumansTeriparatideZoledronic AcidTeriparatideZoledronic AcidFracture preventionMultidisciplinary guidelineOsteoporosis

Identifiers

PMID38564062
PMCPMC10987374
OpenAlexW4393432105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.