Evidence map›Paper›PMID 38563436›Full record

Trial reportMovement disorders clinical practice2024

Effect of a Home-Base Core Stability Exercises in Hereditary Ataxia. A Randomized Controlled Trial. A Pilot Randomized Controlled Trial.

Rosa Cabanas-Valdés, Helena Fernández-Lago, Selma Peláez-Hervás, Laura Serra-Rusiñol, Carlos López-de-Celis, Maria Masbernat-Almenara

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Movement disorders clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Treatment of primary adult-onset neurodegenerative cerebellar ataxias.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rosa Cabanas-ValdésDepartment of Physiotherapy, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Barcelona, Spain.ORCID https://orcid.org/0000-0002-5255-2494
Helena Fernández-LagoDepartment of Nursing and Physiotherapy, Universitat de Lleida, Lleida, Spain.ORCID https://orcid.org/0000-0002-0772-666X
Selma Peláez-HervásServicio de Rehabilitación, Hospital Clínic de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0003-0548-2873
Laura Serra-RusiñolNeurosalud Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-2014-3186
Carlos López-de-CelisDepartment of Physiotherapy, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Barcelona, Spain.ORCID https://orcid.org/0000-0002-9524-4248
Maria Masbernat-AlmenaraDepartment of Nursing and Physiotherapy, Universitat de Lleida, Lleida, Spain.ORCID https://orcid.org/0000-0002-5822-239X
Universitat de Lleida · ESUniversitat Internacional de Catalunya · ESHospital Clínic de Barcelona · ES

Funding

College of Physiotherapists of Catalonia R01/20
6 · The paper itself

Abstract

backgroundCore stability exercises (CSE) have been shown to be effective in improving trunk function in several neurological diseases, but the evidence is scarce on Hereditary Ataxias (HA).

objectiveTo evaluate the effectiveness of a 5-week home-based CSE program in terms of ataxia severity, trunk function, balance confidence, gait speed, lower limb motor function, quality of life, health status and falls rate in HA individuals at short- and long-term.

methodsThis is an assessor-blind randomized controlled clinical trial parallel group 1:1. The individuals were divided in experimental group (EG) performed standard care in addition to CSE, and control group (CG) performed standard care alone. The CSE home-program was conducted 1-h/day, 5-day/week for 5-week. The assessment was performed at baseline, endpoint (5-week), and follow-up (10-week). The primary outcomes were ataxia severity assessed by the Scale for the Assessment and Rating of Ataxia and trunk function assessed by Spanish-version of Trunk Impairment Scale 2.0. The secondary outcomes were balance confidence assessed by Activities-specific Balance Confidence (ABC), gait speed by 4-meter walk test (4-MWT), the lower limb motor function by 30-s sit-to-stand, quality of life by EuroQol 5-dimension 5-level (EQ-5D-5L), health-status by EQ-5D and falls rate.

resultsTwenty-three HA individuals were recruited (51.8 ± 11.10 years). Statistically significant group-time interaction was shown in ABC (F:5.539; P = 0.007), EQ-5D-5L Total (F:4.836; P = 0.013), EQ 5D (F:7.207; P = 0.006).

conclusionsNo statistical differences between groups for ataxia severity and trunk function were observed. However, were differences for balance confidence, gait speed, quality of life, and falls rate in HA individuals.

Indexed as

Exercise TherapyPostural BalanceQuality of LifeAccidental FallsAdultFemaleHumansMaleMiddle AgedPilot ProjectsSeverity of Illness IndexSingle-Blind MethodTreatment Outcomebalancecerebellar ataxiacore stability exerciseshereditary ataxiasquality of lifetrunk function

Identifiers

PMID38563436
PMCPMC11145153
OpenAlexW4393410729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.