Evidence map›Paper›PMID 38563376›Full record

Trial reportThe International journal of social psychiatry2024

Trajectories of intimate partner violence and their relationship to stress among young women in South Africa: An HPTN 068 study.

Nicole K Kelly, Nivedita L Bhushan, Nisha Gottfredson O'Shea, F Xavier Gómez-Olivé, Allison E Aiello, Laura Danielle Wagner, Sumaya Mall, Kathleen Kahn, Audrey E Pettifor, Marie Cd Stoner

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The International journal of social psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Stress-responsive biomarkers and sexual behaviors among young women in rural South Africa.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Nicole K KellyDepartment of Epidemiology, University of North Carolina, Chapel Hill, USA.ORCID 0000-0003-1061-2767
Nivedita L BhushanCenter for Communication and Engagement Research, RTI International, Research Triangle Park, NC, USA.
Nisha Gottfredson O'SheaSubstance Use Prevention, Evaluation, and Research Program, RTI International, Research Triangle Park, NC, USA.
F Xavier Gómez-OlivéMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Allison E AielloDepartment of Epidemiology, Robert N Butler Columbia Aging Center, Mailman School of Public Health, Columbia University, New York, NY, USA.
Laura Danielle WagnerWomen's Global Health Imperative, RTI International, Berkeley, CA, USA.
Sumaya MallDepartment of Epidemiology and Biostatistics, University of the Witwatersrand, Johannesburg, South Africa.
Kathleen KahnMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Audrey E PettiforDepartment of Epidemiology, University of North Carolina, Chapel Hill, USA.
Marie Cd StonerWomen's Global Health Imperative, RTI International, Berkeley, CA, USA.
RTI International · USUniversity of the Witwatersrand · ZAUniversity of North Carolina at Chapel Hill · USColumbia University · US

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
Training in Infectious Disease Epidemiology (TIDE)T32AI070114 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian W Pence · 2007 to 2026
$4.0M
Multilevel Mechanisms of HIV Acquisition in Young South African WomenR01MH110186 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PETTIFOR, AUDREY · 2016 to 2020
$3.4M
Effects of Cash Transfer and Community Mobilization in Young South African WomenR01MH087118 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PETTIFOR, AUDREY · 2009 to 2013
$2.5M
Stress and HIV infection in South African adolescent girls.R21HD106583 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI STONER, MARIE · 2021 to 2022
$436k
NIAID NIH HHS T32 AI070114NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619NICHD NIH HHS R21 HD106583NIMH NIH HHS R01 MH087118NIMH NIH HHS R01 MH110186Wellcome TrustWellcome Trust 058893/Z/99/A; 069683/Z/02/ZWellcome Trust 085477/Z/08/Z; 085477/B/08/Z
6 · The paper itself

Abstract

backgroundOne in four South African women will experience intimate partner violence (IPV) in their lifetime, potentially increasing their biological stress. In South Africa, limited IPV and stress research has utilized multiple timepoints or examined modifying factors. Cash transfers (CTs) are associated with reduced IPV and stress and may be an intervention target.

aimsWe used data-driven methods to identify longitudinal IPV trajectory groups among South African adolescent girls and young women (AGYW), estimate each group's association with stress, and assess modification by a CT.

methodsA total of 2,183 South African AGYW ages 13 to 24 years from the HIV Prevention Trials Network 068 study were randomized to a CT or control group. Physical IPV was measured five times (2011-2017), and stress was captured once (2018-2019). Stress measures included the Cohen Stress Scale and stress biomarkers (C-reactive protein (CRP), cytomegalovirus (CMV), herpes simplex virus type-1 (HSV-1)). Group-based trajectory modeling identified IPV trajectories; ordinal logistic regression estimated the association between trajectory group and stress.

resultsA two-group quadratic trajectory model was identified (higher trajectory group = 26.7% of AGYW; lower trajectory group = 73.3%). In both groups, the probability of IPV increased from ages 13 to 17 years before declining in early adulthood. However, the higher group's probability peaked later and declined gradually. The higher trajectory group was associated with an increased odds of elevated CRP (OR: 1.41, 95% CI [1.11, 1.80]), but not with other stress measures. The CT modified the relationship with CMV: a positive association was observed among the usual care arm (OR: 1.59, 95% CI [1.11, 2.28]) but not the CT arm (OR: 0.85, 95% CI [0.61, 1.19]).

conclusionsSustained IPV risk during adolescence was associated with elevated CRP in young adulthood. The relationship between IPV and elevated CMV was attenuated among those receiving a CT, suggesting that CTs could possibly reduce biological stress due to IPV.

Indexed as

Intimate Partner ViolenceStress, PsychologicalAdolescentFemaleHumansLogistic ModelsLongitudinal StudiesSouth AfricaYoung Adultadolescent girls and young womencash transfersgroup-based trajectory modelsIntimate partner violenceSouth Africastress

Identifiers

PMID38563376
PMCPMC11323414
OpenAlexW4393418577

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.