Evidence map›Paper›PMID 38563189›Full record

ArticleEuropean journal of neurology2024

Association of diabetes mellitus with dementia- and non-dementia-related mortality amongst women: a secondary competing risks analysis of the California Teachers Study.

Cathleen Morgan, Bradon Annegers, Matthew K Taylor, Sara Shuger Fox, Tyler J Titcomb

Abstract read
In one paragraph

Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cathleen MorganDepartment of Kinesiology, Central College, Pella, Iowa, USA.
Bradon AnnegersDepartment of Kinesiology, Central College, Pella, Iowa, USA.
Matthew K TaylorDepartment of Dietetics and Nutrition, Kansas University Medical Center, Kansas City, Kansas, USA.
Sara Shuger FoxDepartment of Kinesiology, Central College, Pella, Iowa, USA.
Tyler J TitcombDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-8162-4768

Funding

Diabetes Research Training Program Diversity SupplementT32DK112751 · NIDDK · UNIVERSITY OF IOWA · PI Andrew W Norris · 2017 to 2026
$4.8M
High Glycemic Diet and Alzheimer's RiskK01AG065487 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI TAYLOR, MATTHEW · 2020 to 2024
$654k
NIA NIH HHS K01 AG065487NIA NIH HHS K01AG065487NIDDK NIH HHS T32 DK112751NIDDK NIH HHS T32DK112751-05
6 · The paper itself

Abstract

background and purposeThe prevalence of dementia is rapidly increasing. Attempts to further understand modifiable risk factors such as diabetes mellitus (DM) are urgently needed to inform public health policies for prevention. Thus, the objective of the current study was to assess the relationship between DM and risk of dementia and non-dementia mortality amongst women in the California Teachers Study prospective cohort.

methodsWomen (n = 124,509) aged 22-104 years at baseline were included. DM was ascertained from self-reported questionnaires and hospital-linked records. Dementia-related deaths were ascertained from state and national records. Competing risk regression models were used to estimate cause-specific hazard ratios and 95% confidence intervals for the association of DM with dementia- and non-dementia-related mortality.

resultsThere were 10,511 total DM cases and 3625 deaths due to dementia over a mean of 21.3 years of follow-up. Fully adjusted cause-specific hazard ratios of the association with DM were 2.26 (2.01, 2.55) for dementia-related and 1.97 (1.89, 2.05) for the competing risk of non-dementia-related mortality. This association was strongest amongst participants with incident DM, younger age at baseline and higher alcohol consumption or who were overweight.

conclusionsIn the California Teachers Study, women with DM had increased risk of mortality due to both dementia and non-dementia causes; however, the risk of mortality due to dementia was elevated compared to non-dementia causes only amongst participants with incident DM.

Indexed as

DementiaDiabetes MellitusAdultAgedAged, 80 and overCaliforniaFemaleHumansMiddle AgedProspective StudiesRisk FactorsSchool TeachersYoung Adultdementiadiabetesepidemiologymortalitywomen

Identifiers

PMID38563189
PMCPMC11161306

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.