Evidence map›Paper›PMID 38563112›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

HPV DNA Testing and Mobile Colposcopy for Cervical Precancer Screening in HIV Positive Women: A Comparison Between Two Settings in Ghana and Recommendation for Screening.

Kofi Effah, Richard Anthony, Ethel Tekpor, Joseph E Amuah, Comfort M Wormenor, Georgina Tay, Smith E Y Kraa, Angela M Katso, Christiana A Akonnor, Seyram Kemawor and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
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  6. Alleviating the Global Burden of Cancer Through Prevention and Early Detection.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Kofi EffahCatholic Hospital, Battor, Volta Region, Ghana.
Richard AnthonyTema General Hospital, Tema, Ghana.
Ethel TekporCatholic Hospital, Battor, Volta Region, Ghana.
Joseph E AmuahCatholic Hospital, Battor, Volta Region, Ghana.
Comfort M WormenorCatholic Hospital, Battor, Volta Region, Ghana.
Georgina TayCatholic Hospital, Battor, Volta Region, Ghana.
Smith E Y KraaCatholic Hospital, Battor, Volta Region, Ghana.
Angela M KatsoTema General Hospital, Tema, Ghana.
Christiana A AkonnorTema General Hospital, Tema, Ghana.
Seyram KemaworCatholic Hospital, Battor, Volta Region, Ghana.
Stephen DanyoCatholic Hospital, Battor, Volta Region, Ghana.
Bernard H AtugubaCatholic Hospital, Battor, Volta Region, Ghana.
Nana Owusu M EsselCatholic Hospital, Battor, Volta Region, Ghana.ORCID 0000-0001-5494-5411
Patrick K AkakpoDepartment of Pathology, School of Medical Sciences, Clinical Teaching Center, University of Cape Coast, Cape Coast, Ghana.
Catholic University College of Ghana · GHUniversity of Alberta · CAUniversity of Cape Coast · GHUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWomen living with HIV (WLHIV) have higher prevalence and persistence rates of high-risk human papillomavirus (hr-HPV) infection with a six-fold increased risk of cervical cancer. Thus, more frequent screening is recommended for WLHIV.

objectivesThis retrospective descriptive cross-sectional study was conducted to investigate and compare the prevalence of hr-HPV infection and abnormal findings on mobile colposcopy in two cohorts of WLHIV following cervical screening in rural and urban settings in Ghana.

methodsThrough the mPharma 10 000 Women Initiative, WLHIV were screened via concurrent hr-HPV DNA testing (MA-6000; Sansure Biotech Inc., Hunan, China) and visual inspection (Enhanced Visual Assessment [EVA] mobile colposcope; MobileODT, Tel Aviv, Israel) by trained nurses. The women were screened while undergoing routine outpatient reviews at HIV clinics held at the Catholic Hospital, Battor (rural setting) and Tema General Hospital (urban setting), both in Ghana.

resultsTwo-hundred and fifty-eight WLHIV were included in the analysis (rural, n = 132; urban, n = 126). The two groups were comparable in terms of age, time since HIV diagnosis, and duration of treatment for HIV. The hr-HPV prevalence rates were 53.7% (95% CI, 45.3-62.3) and 48.4% (95% CI, 39.7-57.1) among WLHIV screened in the rural vs urban settings (

conclusionsThere is a high prevalence of hr-HPV among WLHIV in both rural and urban settings in this study in Ghana. Concurrent HPV DNA testing with a visual inspection method (colposcopy/VIA) reduces loss to follow-up compared to performing HPV DNA testing as a standalone test and recalling hr-HPV positive women for follow up with a visual inspection method. Concurrent HPV DNA testing and a visual inspection method may also pick up precancerous cervical lesions that are hr-HPV negative and may be missed if HPV DNA testing is performed alone.

Indexed as

HIV InfectionsPapillomavirus InfectionsPrecancerous ConditionsUterine Cervical DysplasiaUterine Cervical NeoplasmsColposcopyCross-Sectional StudiesEarly Detection of CancerFemaleGhanaHumansMass ScreeningPapillomaviridaePregnancyRetrospective Studiescervical precancer screeningHIVhuman papillomavirus DNA testinghuman papillomavirus infectionmobile colposcopyrural-urban disparities

Identifiers

PMID38563112
PMCPMC10989037
OpenAlexW4393434681

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.