Evidence map›Paper›PMID 38563065›Full record

ArticleAnnals of the Royal College of Surgeons of England2025

A diagnosis of syphilis following a radical circumcision for suspected penile cancer.

K H Pang, A Haider, A Freeman, P Hadway, C Bunker, A Muneer, H M Alnajjar

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Annals of the Royal College of Surgeons of England, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

K H PangUniversity College London Hospitals NHS Foundation Trust, UK.
A HaiderUniversity College London Hospitals NHS Foundation Trust, UK.
A FreemanUniversity College London Hospitals NHS Foundation Trust, UK.
P HadwayUniversity College London Hospitals NHS Foundation Trust, UK.
C BunkerUniversity College London Hospitals NHS Foundation Trust, UK.
A MuneerUniversity College London Hospitals NHS Foundation Trust, UK.
H M AlnajjarUniversity College London Hospitals NHS Foundation Trust, UK.
University College London · GBUniversity College London Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of a 70-year-old gentleman who was referred to our tertiary 2-week-wait penile cancer clinic with a penile mass that was ulcerated, painful and discharging. This was suspicious for penile cancer and a radical circumcision was performed to remove the diseased foreskin en bloc with the lesion that was arising from the inner foreskin. Histopathology did not reveal cancer; however, we identified spirochaetes in keeping with syphilis. This was confirmed on serology. The patient was referred to the genitourinary medicine team and treated with antibiotics. This case demonstrates a rare presentation of genital syphilis in an elderly gentleman initially referred with concerns of penile cancer. Although, rare, especially in this age group, syphilis should be considered as a differential diagnosis in a patient presenting with an ulcerated, discharging, firm penile mass, especially given that the incidence of syphilis has been rising in recent years.

Indexed as

Circumcision, MalePenile NeoplasmsSyphilisAgedAnti-Bacterial AgentsDiagnosis, DifferentialHumansMaleAnti-Bacterial AgentsCircumcisionLichen sclerosusMultidisciplinaryPenile lesionSexually transmitted infectionSyphilis

Identifiers

PMID38563065
PMCPMC11957837
OpenAlexW4393436905

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.