Evidence map›Paper›PMID 38563005›Full record

ArticlePeerJ2024

Identification, validation and quantification of thymoquinone in conjunction with assessment of bioactive possessions and GC-MS profiling of pharmaceutically valuable crop Nigella (

Ravi Y, Irene Vethamoni Periyanadar, Shailendra Nath Saxena, Raveendran Muthurajan, Velmurugan Sundararajan, Santhanakrishnan Vichangal Pridiuldi, Sumer Singh Meena, Ashoka Narayana Naik, C B Harisha, Honnappa Asangi and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Ravi YICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.
Irene Vethamoni PeriyanadarHC & RI, Tamil Nadu Agricultural University, Coimbatore, India.
Shailendra Nath SaxenaICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.
Raveendran MuthurajanCentre for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India.
Velmurugan SundararajanHC & RI, Tamil Nadu Agricultural University, Coimbatore, India.
Santhanakrishnan Vichangal PridiuldiHC & RI, Tamil Nadu Agricultural University, Coimbatore, India.
Sumer Singh MeenaICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.
Ashoka Narayana NaikCOH, Sirsi, University of Horticultural Sciences, Bagalkote, Sirsi, Karnataka, India.
C B HarishaICAR-National Institute of Abiotic Stress Management, Pune, Maharastra, India.
Honnappa AsangiICAR-Indian Institute of Spices Research, Regional Station, Appangala, Madikeri, Karnataka, India.
Sharda ChoudharyICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.
Ravindra SinghICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.ORCID 0000-0003-2476-3566
Yallappa DengeruAEC & RI, Tamil Nadu Agricultural University, Coimbatore, India.
Kavan Kumar VDepartment of Renewable Energy Engineering, CTAE, MPUAT, Udaipur, India.ORCID 0000-0002-1940-8677
Narottam Kumar MeenaICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.
Ram Swaroop MeenaICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.
Arvind Kumar VermaICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India.
National Research Centre on Seed Spices · INTamil Nadu Agricultural University · INIndian Institute of Spices Research · INMaharana Pratap University of Agriculture and Technology · INNational Institute of Abiotic Stress Management · INUniversity of Horticultural Sciences Bagalkote · IN

Funding

CoimbatoreHorticultural College and Research Institute (HC&RI)IndiaTamil NaduTamil Nadu Agricultural University
6 · The paper itself

Abstract

Background: Plants have been pivotal in traditional and modern medicine globally, with historical evidence supporting their therapeutic applications. Nigella ( Methodology: This study specifically examines the pharmacological potential of Results: The research revealed that the Ajmer nigella-20 variety stands out, exhibiting elevated levels of thymoquinone (0.20 ± 0.07%), antioxidants (76.18 ± 1.78%), and substantial quantities of total phenols (31.85 ± 0.97 mg GAEg Conclusion: The observed variations among Nigella varieties indicate the Ajmer nigella-20 variety as particularly promising for thymoquinone and bioactive compound extraction. This study underscores Nigella's potential as a source of pharmacologically active compounds, highlighting the need for further exploration in therapeutic applications.

Indexed as

BenzoquinonesNigellaNigella sativaFlavonoidsGas Chromatography-Mass SpectrometryPlant ExtractsBenzoquinonesFlavonoidsPlant ExtractsthymoquinoneAgricultural scienceGeneticsHPLCMedicinal plantsOmics technologyPlant science

Identifiers

PMID38563005
PMCPMC10984176
OpenAlexW4393316833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.