Evidence map›Paper›PMID 38562941›Full record

ArticleFrontiers in immunology2024

JNK signaling mediates acute rejection via activating autophagy of CD8

Xiaowen Wang, Wenfeng Zhu, Haoqi Chen, Xuejiao Li, Wenjie Zheng, Yuan Zhang, Ning Fan, Xiaolong Chen, Genshu Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Xiaowen Wang *Department of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Wenfeng Zhu *Department of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Haoqi Chen *Department of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Xuejiao LiGuangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Wenjie ZhengDepartment of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yuan ZhangState Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Ning FanState Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiaolong ChenDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Genshu WangState Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Third Affiliated Hospital of Sun Yat-sen University · CNGuangdong Provincial Hospital of Traditional Chinese Medicine · CNFirst Affiliated Hospital of Jinan University · CNGuangzhou University of Chinese Medicine · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute rejection (AR) after liver transplantation (LT) remains an important factor affecting the prognosis of patients. CD8 Methods: Human liver biopsy specimens of AR after orthotopic LT were collected to assess the relationship between JNK and CD8 Results: The expression of JNK is positive correlated with the autophagy level of CD8 Conclusion: JNK signaling promoted CD8

Indexed as

Liver TransplantationAnimalsApoptosisAutophagyCD8-Positive T-LymphocytesHumansMAP Kinase Signaling SystemRatsacute rejectionautophagyCD8+ T cellsJNK signalingliver transplantation

Identifiers

PMID38562941
PMCPMC10982410
OpenAlexW4392923664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.