Evidence map›Paper›PMID 38562907›Full record

ArticlebioRxiv : the preprint server for biology2024

Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.

Jeffrey Wang, Jung Min Suh, Brian J Woo, Albertas Navickas, Kristle Garcia, Keyi Yin, Lisa Fish, Taylor Cavazos, Benjamin Hänisch, Daniel Markett and 6 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 3 countries.

Jeffrey WangDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.
Jung Min SuhDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.
Brian J WooDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.
Albertas NavickasDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0003-0016-2643
Kristle GarciaDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-9868-8397
Keyi YinDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.
Lisa FishDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0001-9184-0512
Taylor CavazosBiological and Medical Informatics, University of California San Francisco, San Francisco, CA, 94158, USA.ORCID 0000-0003-3537-2608
Benjamin HänischDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.
Daniel MarkettDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.
Shaorong YuDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.
Gillian HirstDepartment of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-4502-0035
Lamorna Brown-SwigartDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Laura J EssermanDepartment of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.
Laura J van 't VeerDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Hani GoodarziDepartment of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-9648-8949
University of California, San Francisco · USCentre National de la Recherche Scientifique · FR

Funding

The I SPY 2.2 TRIAL: Evolving to Imaging and Molecular Biomarker Response Directed Adaptive Sequential Treatment to Optimize Breast Cancer OutcomesP01CA210961 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nola M. Hylton-Watson · 2017 to 2026
$22.9M
MOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0M
Restorative practice in repairing harm and promoting safe and inclusive practices in the laboratory.T32GM136547 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Adrian Erlebacher, Anita Sil · 2020 to 2026
$4.5M
An antisense RNA-mediated regulatory program that drives cancer metastasisR01CA240984 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOODARZI, HANI · 2019 to 2023
$2.5M
The RNA structural code underlying pathological regulation of RNA splicing in metastasisR01CA244634 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOODARZI, HANI · 2021 to 2025
$1.8M
Illumina NovaSeq 6000 Sequencing SystemS10OD028511 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOW, ERIC D · 2020 to 2020
$583k
NCI NIH HHS P01 CA210961NCI NIH HHS R01 CA240984NCI NIH HHS R01 CA244634NIAID NIH HHS T32 AI007334NIGMS NIH HHS T32 GM136547NIH HHS S10 OD028511
6 · The paper itself

Abstract

From extrachromosomal DNA to neo-peptides, the broad reprogramming of the cancer genome leads to the emergence of molecules that are specific to the cancer state. We recently described orphan non-coding RNAs (oncRNAs) as a class of cancer-specific small RNAs with the potential to play functional roles in breast cancer progression

Identifiers

PMID38562907
PMCPMC10983903
OpenAlexW4393034299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.