Evidence map›Paper›PMID 38562528›Full record

ArticleFrontiers in radiology2024

Arterial spin labeled perfusion MRI for the assessment of radiation-treated meningiomas.

Paul Manning, Shanmukha Srinivas, Divya S Bolar, Matthew K Rajaratnam, David E Piccioni, Carrie R McDonald, Jona A Hattangadi-Gluth, Nikdokht Farid

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Paul ManningDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Shanmukha SrinivasCenter for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States.
Divya S BolarDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
Matthew K RajaratnamCenter for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States.
David E PiccioniDepartment of Neurosciences, University of California, San Diego, San Diego, CA, United States.
Carrie R McDonaldCenter for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States.
Jona A Hattangadi-GluthDepartment of Radiation Medicine and Applied Sciences, University of California, San Diego, San Diego, CA, United States.
Nikdokht FaridDepartment of Radiology, University of California, San Diego, San Diego, CA, United States.
University of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Conventional contrast-enhanced MRI is currently the primary imaging technique used to evaluate radiation treatment response in meningiomas. However, newer perfusion-weighted MRI techniques, such as 3D pseudocontinuous arterial spin labeling (3D pCASL) MRI, capture physiologic information beyond the structural information provided by conventional MRI and may provide additional complementary treatment response information. The purpose of this study is to assess 3D pCASL for the evaluation of radiation-treated meningiomas. Methods: Twenty patients with meningioma treated with surgical resection followed by radiation, or by radiation alone, were included in this retrospective single-institution study. Patients were evaluated with 3D pCASL and conventional contrast-enhanced MRI before and after radiation (median follow up 6.5 months). Maximum pre- and post-radiation ASL normalized cerebral blood flow (ASL-nCBF) was measured within each meningioma and radiation-treated meningioma (or residual resected and radiated meningioma), and the contrast-enhancing area was measured for each meningioma. Wilcoxon signed-rank tests were used to compare pre- and post-radiation ASL-nCBF and pre- and post-radiation area. Results: All treated meningiomas demonstrated decreased ASL-nCBF following radiation ( Conclusions: ASL perfusion may provide complementary treatment response information in radiation-treated meningiomas. This complementary information could aid clinical decision-making and provide an additional endpoint for clinical trials.

Indexed as

arterial spin labeledASLCBFcerebral blood flowmeningiomaperfusion

Identifiers

PMID38562528
PMCPMC10982483
OpenAlexW4392925546

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.