Trial reportDrug design, development and therapy2024
The Safety and Efficacy of Remimazolam Compared to Dexmedetomidine for Awake Tracheal Intubation by Flexible Bronchoscopy: A Randomized, Double-Blind, Controlled Trial.
Trial report in Drug design, development and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Pooled it
- Remimazolam compared to dexmedetomidine on the incidence of hypotension in middle aged and elderly patients undergoing general anesthesia: a systematic review and meta-analysis.BMC anesthesiology · 2025Pooled it
- Sedation for awake tracheal intubation: A systematic review and network meta-analysis.Anaesthesia · 2025Pooled it
- Trial
- Efficacy and safety of remimazolam combined with remifentanil for sedation during awake fiberoptic intubation: a randomized controlled trial.Annals of medicine · 2025Trial
- Low-Dose Dexmedetomidine Attenuates the Dose Requirement of Propofol for Suppression of Body Movement in Patients Undergoing Operative Hysteroscopy.Drug design, development and therapy · 2025Trial
- Efficacy and Safety of Remimazolam versus Dexmedetomidine and Midazolam in Awake Endotracheal Intubation for Difficult Airway Patients: A Randomized Controlled Study.Drug design, development and therapy · 2025Trial
- Efficacy and safety of dexmedetomidine in adult patients undergoing bronchoscopy: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Review
- Comparative efficacy and safety of remimazolam vs. dexmedetomidine: A systematic review and meta-analysis.Biomedical reports · 2026Article
- Comparative Safety of Intravenous Sedatives for Bronchoscopy: A Bayesian Network Meta-Analysis.Yonsei medical journal · 2026Article
- Comparison of the safety and efficacy of remimazolamFrontiers in pharmacology · 2026Article
- Preserving Airway Reflexes During Awake Intubation: A Cautionary Note on Deep Sedation Protocols [Response to Letter].Drug design, development and therapy · 2026Article
- Anesthetic management of giant thyroid tumor with cardiac comorbidity causing tracheal compression: a case report.Journal of medical case reports · 2025Article
- Article
- Comparison of intravenous nalbuphine and dexmedetomidine in combination with lidocaine aerosol inhalation in awake direct laryngoscopy: a randomized, double-blind, placebo-controlled trial.Perioperative medicine (London, England) · 2024Article
- Comparison of Remimazolam and Dexmedetomidine for Sedation in Awake Endotracheal Intubation in Scoliosis Surgery: A Retrospective Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Remimazolam and Its Place in the Current Landscape of Procedural Sedation and General Anesthesia.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Remimazolam is a novel ultra-short-acting benzodiazepine sedative that has the potential to be an alternative for procedural sedation due to its rapid sedation and recovery, no accumulation effect, stable hemodynamics, minimal respiratory depression, anterograde amnesia effect, and specific antagonist. Here, we aimed to compare the safety and efficacy of remimazolam with dexmedetomidine for awake tracheal intubation by flexible bronchoscopy (ATI-FB). Methods: Ninety patients scheduled for ATI-FB were randomly divided into three groups, each consisting of 30 cases: dexmedetomidine 0.6 µg/kg + sufentanil (group DS), remimazolam 0.073 mg/kg + sufentanil (group R Results: The success rates of sedation in groups R Conclusion: In conclusion, both DS and R
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.