Evidence map›Paper›PMID 38562428›Full record

ArticleFrontiers in neurology2024

Spectral exponent assessment and neurofilament light chain: a comprehensive approach to describe recovery patterns in stroke.

Jacopo Lanzone, Aida Zulueta, Marilisa Boscarino, Matteo Gallotta, Maria Rosaria Argentieri, Alessandro Viganò, Simone Sarasso, Michele A Colombo, Sasha D'Ambrosio, Christian Lunetta and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jacopo LanzoneIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of the Milano Institute, Milan, Italy.
Aida ZuluetaIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of the Milano Institute, Milan, Italy.
Marilisa BoscarinoIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of the Milano Institute, Milan, Italy.
Matteo GallottaIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of the Milano Institute, Milan, Italy.
Maria Rosaria ArgentieriIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of the Milano Institute, Milan, Italy.
Alessandro ViganòIRCCS Fondazione Don Carlo Gnocchi, ONLUS, Milan, Italy.
Simone SarassoDepartment of Biomedical and Clinical Sciences, Università Degli Studi di Milano, Milan, Italy.
Michele A ColomboDepartment of Biomedical and Clinical Sciences, Università Degli Studi di Milano, Milan, Italy.
Sasha D'AmbrosioIRCCS Fondazione Don Carlo Gnocchi, ONLUS, Milan, Italy.
Christian LunettaIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of the Milano Institute, Milan, Italy.
Eugenio ParatiIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of the Milano Institute, Milan, Italy.
Istituti Clinici Scientifici Maugeri · ITUniversity of Milan · ITDon Carlo Gnocchi Foundation · ITEpilepsy Research UK · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Understanding the residual recovery potential in stroke patients is crucial for tailoring effective neurorehabilitation program Methods: We enrolled 13 patients (4 female, mean age 74.7 ± 8.8) who underwent stroke in the previous month and were hospitalized for 2-months rehabilitation. Patients underwent blood withdrawal, clinical evaluation and high-definition EEG at T1 (first week of rehabilitation) and at T2 (53 ± 10 days after). We assessed the levels of NfL and we analyzed the EEG signal extracting Spectral Exponent (SE) values. We compared our variables between the two timepoint and between cortical and non-cortical strokes. Results: We found a significant difference in the symmetry of SE values between cortical and non-cortical stroke at both T1 ( Conclusion: We present proof of concept of a promising approach for the characterization of different recovery patterns in stroke patients.

Indexed as

biomarkersEEGneurofilamentrehabilitationstroke

Identifiers

PMID38562428
PMCPMC10982436
OpenAlexW4392925373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.