Evidence map›Paper›PMID 38562339›Full record

ArticleCureus2024

Splenic Marginal Zone Lymphoma in a Patient With Antiphospholipid Syndrome Treated With Rituximab: A Case Report.

Laxman Wagle, Dhiraj R Regmi, Samaj Adhikari, Parmartha Basnyat, Abhishek Kalla

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Laxman WagleInternal Medicine, Ascension Saint Agnes Hospital, Baltimore, USA.
Dhiraj R RegmiInternal Medicine, Tanahun Sewa Hospital, Tanahun, NPL.
Samaj AdhikariInternal Medicine, Interfaith Medical Center, Brooklyn, USA.
Parmartha BasnyatInternal Medicine, Ascension Saint Agnes Hospital, Baltimore, USA.
Abhishek KallaHematology and Oncology, Ascension Saint Agnes Hospital, Baltimore, USA.
Tân Tạo University · VNInterfaith Medical Center · USSaint Agnes Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splenic marginal zone lymphoma (SMZL) usually presents with splenomegaly or symptoms related to cytopenia. We report a case of a 56-year-old female with previously diagnosed antiphospholipid syndrome (APS) on warfarin therapy who initially presented with abdominal pain and was found to have massive splenomegaly and splenic infarction on CT imaging. Initial clinical presentations and imaging findings were attributed to the subtherapeutic coagulation profile. The patient was later diagnosed with SMZL following workup for pancytopenia including bone marrow biopsy, flow cytometry, and PET scan. Cytopenias, splenomegaly, and abnormal metabolic activity in the spleen on the PET scan improved after treatment with four cycles of weekly rituximab. Our report presents a case of a patient with longstanding APS presenting with splenic infarction and pancytopenia who was subsequently diagnosed with SMZL and successfully treated with rituximab.

Indexed as

antiphospholipid antibody (apla)antiphospholipid antibody syndrome (aps)non-hodgkin’s lymphomasrituximab therapysplenic marginal zone lymphoma

Identifiers

PMID38562339
PMCPMC10983820
OpenAlexW4392347899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.