Evidence map›Paper›PMID 38562310›Full record

ArticleBrain communications2024

Hippocampal hyperphosphorylated tau-induced deficiency is rescued by L-type calcium channel blockade.

Chelsea A Crossley, Tamunotonye Omoluabi, Sarah E Torraville, Sarah Duraid, Aida Maziar, Zia Hasan, Vishaal Rajani, Kanae Ando, Johannes W Hell, Qi Yuan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Sex and life experience shape locus coeruleus pretangle tau pathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Chelsea A CrossleyBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Tamunotonye OmoluabiBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Sarah E TorravilleBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Sarah DuraidBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Aida MaziarBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Zia HasanBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Vishaal RajaniBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.
Kanae AndoDepartment of Biological Sciences, School of Science, Tokyo Metropolitan University, Tokyo, 192-0397, Japan.ORCID https://orcid.org/0000-0002-3956-276X
Johannes W HellDepartment of Pharmacology, School of Medicine, University of California at Davis, Davis, CA 95616, USA.
Qi YuanBiomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL A1B 3V6, Canada.ORCID https://orcid.org/0000-0002-9837-8495
Memorial University of Newfoundland · CATokyo Metropolitan University · JPUniversity of California, Davis · US

Funding

Dysregulation of Cav1.2 by beta amyloid peptideRF1AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2022 to 2024
$1.7M
NIA NIH HHS RF1 AG055357
6 · The paper itself

Abstract

Aging and Alzheimer's disease are associated with chronic elevations in neuronal calcium influx

Indexed as

Alzheimer’s diseasehippocampusL-type calcium channelspatial learningtau

Identifiers

PMID38562310
PMCPMC10984573
OpenAlexW4393055235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.