ArticlePlant physiology2024
Key transcription factors regulate fruit ripening and metabolite accumulation in tomato.
Article in Plant physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 65 citations in OpenAlex.
- Maize ZmbZIP92 transcription factor positively regulates drought tolerance inPlant signaling & behavior · 2026Article
- Profile of the Bioactive Compounds, Minerals, Antioxidant and Antimicrobial Properties of Coloured Cherry Tomatoes at Different Stages of Ripeness.Foods (Basel, Switzerland) · 2026Article
- Regulation of the growth-to-ripening transition in tomato fruits by energy charge involving SlATP-PRT and SlAPRT1.Molecular horticulture · 2026Article
- SlGRF1 mediates gibberellin signaling to control cut-budding in tomato.Journal of integrative plant biology · 2026Article
- DNA hypomethylation enables the transcriptional repressor SlSPL-CNR to control fruit flavor ester biosynthesis.Nature communications · 2026Article
- Larix gmelinii UGPase enhances vegetative growth in transgenic poplar through an HYH-mediated positive feedback loop.Plant cell reports · 2026Article
- Bioconversion of carotenoids into high-value crocins using a marine sponge carotenoid cleavage dioxygenase.The New phytologist · 2026Article
- Tandem MADS-Box Genes FUL2 and MADS1 Form a Regulatory Module to Repress Serotonin Biosynthesis via Direct ASMT5 Activation in Tomato Fruit.Plant biotechnology journal · 2026Article
- Salt-stress-induced tomato sweetening involves an SlSnRK2.6-SlZHD8 sugar accumulation cascade triggered by root-derived abscisic acid.The EMBO journal · 2026Article
- Integrated Transcriptome and Metabolome Analysis of Fruit Quality Variation in 'Sweet100' Tomato Across Different Growth Stages.Foods (Basel, Switzerland) · 2026Article
- Dynamic chromatin regulatory programs of sucrose and citric acid metabolism during fruit ripening in Citrus.The Plant cell · 2026Article
- Applications of omics in deciphering the unique traits of durian, the king of fruits.Plant molecular biology · 2026Review
- Light regulates tomato fruit metabolome via SlDML2-mediated global DNA demethylation.Journal of integrative plant biology · 2026Article
- Advances in the Regulatory Mechanism of Enzymes Involved in Soluble Sugar Metabolism in Fruits.Plants (Basel, Switzerland) · 2026Review
- Transcriptome-based resistance analysis of susceptible and resistant tomato cultivars againstFrontiers in plant science · 2026Article
- Exogenous proline regulates the antioxidation system and fruit quality of cherry tomatoes under chilling storage: Integrated physiological, metabolomic, and transcriptomic study.Food chemistry. Molecular sciences · 2025Article
- Targeted mutagenesis ofaBIOTECH · 2025Article
- Integrated transcriptomic and metabolomic analyses delineate the biosynthetic pathways of functional components in maturingFood chemistry. Molecular sciences · 2025Article
- Transcriptional control of tomato fruit development and ripening.Journal of experimental botany · 2025Review
- Metabolic Profiling and Functional Metabolite Distribution in Colored Tomatoes.Foods (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Fruit ripening is a complex process involving dynamic changes to metabolites and is controlled by multiple factors, including transcription factors (TFs). Several TFs are reportedly essential regulators of tomato (Solanum lycopersicum) fruit ripening. To evaluate the effects of specific TFs on metabolite accumulation during fruit ripening, we combined CRISPR/Cas9-mediated mutagenesis with metabolome and transcriptome analyses to explore regulatory mechanisms. Specifically, we generated various genetically engineered tomato lines that differed regarding metabolite contents and fruit colors. The metabolite and transcript profiles indicated that the selected TFs have distinct functions that control fruit metabolite contents, especially carotenoids and sugars. Moreover, a mutation to ELONGATED HYPOCOTYL5 (HY5) increased tomato fruit fructose and glucose contents by approximately 20% (relative to the wild-type levels). Our in vitro assay showed that HY5 can bind directly to the G-box cis-element in the Sugars Will Eventually be Exported Transporter (SWEET12c) promoter to activate expression, thereby modulating sugar transport. Our findings provide insights into the mechanisms regulating tomato fruit ripening and metabolic networks, providing the theoretical basis for breeding horticultural crops that produce fruit with diverse flavors and colors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.