Evidence map›Paper›PMID 38561770›Full record

ArticleBMC veterinary research2024

In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms.

Mihai-Horia Băieş, Vlad-Dan Cotuţiu, Marina Spînu, Attila Mathe, Anamaria Cozma-Petruț, Sorana D Bolboacǎ, Ricarda Margaret Engberg, Anne Collin, Vasile Cozma

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Low-ThujoneMolecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Effect of herbal preparationOpen veterinary journal · 2025
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  4. Journal of advanced veterinary and animal research · 2025
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Mihai-Horia BăieşDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 3-5 Mǎnǎştur Street, 400372, Cluj-Napoca-Napoca, Romania.
Vlad-Dan CotuţiuDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 3-5 Mǎnǎştur Street, 400372, Cluj-Napoca-Napoca, Romania.
Marina SpînuDepartment of Infectious Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 3-5 Mǎnǎştur Street, 400372, Cluj-Napoca-Napoca, Romania.
Attila MatheAgricultural Research and Development Station of Turda, 27 Agriculturii Street, 401100, Turda, Romania.
Anamaria Cozma-PetruțDepartment of Bromatology, Hygiene, Nutrition, Faculty of Pharmacy, "Iuliu Haţieganu" University of Medicine and Pharmacy, 6 Pasteur Street, 400349, Cluj-Napoca-Napoca, Romania. anamaria.cozma@umfcluj.ro.
Sorana D BolboacǎDepartment of Medical Informatics and Biostatistics, "Iuliu Haţieganu" University of Medicine and Pharmacy, 6 Louis Pasteur Street, 400349, Cluj-Napoca-Napoca, Romania.
Ricarda Margaret EngbergDepartment of Animal and Veterinary Sciences, Aarhus University, 20 Blichers Allé, 8830, Tjele, Denmark.
Anne CollinINRAE, Université de Tours, BOA, 37380, Nouzilly, France.
Vasile CozmaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 3-5 Mǎnǎştur Street, 400372, Cluj-Napoca-Napoca, Romania.
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · ROIuliu Hațieganu University of Medicine and Pharmacy · ROAarhus University · DKBiologie des Oiseaux et Aviculture · FR

Funding

European Union's Horizon 2020 research and innovation programme, PPILOW project N°816172
6 · The paper itself

Abstract

backgroundEthno-veterinary practices could be used as a sustainable developmental tool by integrating traditional phytotherapy and husbandry. Phytotherapeutics are available and used worldwide. However, evidence of their antiparasitic efficacy is currently very limited. Parasitic diseases have a considerable effect on pig production, causing economic losses due to high morbidity and mortality. In this respect, especially smallholders and organic producers face severe challenges. Parasites, as disease causing agents, often outcompete other pathogens in such extensive production systems. A total of 720 faecal samples were collected in two farms from three age categories, i.e. weaners, fatteners, and sows. Flotation (Willis and McMaster method), modified Ziehl-Neelsen stained faecal smear, centrifugal sedimentation, modified Blagg technique, and faecal cultures were used to identify parasites and quantify the parasitic load.

resultsThe examination confirmed the presence of infections with Eimeria spp., Cryptosporidium spp., Balantioides coli (syn. Balantidium coli), Ascaris suum, Oesophagostomum spp., Strongyloides ransomi, and Trichuris suis, distributed based on age category. A dose of 180 mg/kg bw/day of Allium sativum L. and 90 mg/kg bw/day of Artemisia absinthium L. powders, administered for 10 consecutive days, revealed a strong, taxonomy-based antiprotozoal and anthelmintic activity.

conclusionsThe results highlighted the therapeutic potential of both A. sativum and A. absinthium against gastrointestinal parasites in pigs. Their therapeutic effectiveness may be attributed to the content in polyphenols, tocopherols, flavonoids, sterols, sesquiterpene lactones, and sulfoxide. Further research is required to establish the minimal effective dose of both plants against digestive parasites in pigs.

Indexed as

Anti-Infective AgentsArtemisia absinthiumCryptosporidiosisCryptosporidiumGarlicIntestinal Diseases, ParasiticParasitesSwine DiseasesAnimalsAntiparasitic AgentsFarmsFecesFemalePrevalenceSwineAnti-Infective AgentsAntiparasitic AgentsGarlicGastrointestinal parasitesLow-input farmsWormwood

Identifiers

PMID38561770
PMCPMC10983701
OpenAlexW4393387642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.