Evidence map›Paper›PMID 38561702›Full record

ArticleBMC pediatrics2024

Exploring the complex dynamics of BMI, age, and physiological indicators in early adolescents.

Ning Ding, Suyun Li, Han Zhou, Zhenchuang Tang, Tianlin Gao, Meina Tian, Changqing Liu, Xiaoyan Luo, Hongtong Chen, Lianlong Yu and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Ning DingDepartment of Pediatrics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Suyun LiShandong Center for Disease Control and Prevention, Ji'nan, Jinan, Shandong, China.
Han ZhouShandong Center for Disease Control and Prevention, Ji'nan, Jinan, Shandong, China.
Zhenchuang TangInstitute of Food and Nutrition Development, Ministry of Agriculture and Rural Affairs, Beijing, China.
Tianlin GaoSchool of Public Health, Qingdao University, Qingdao, China.
Meina TianHebei Center for Disease Control and Prevention, Shijiazhuang, Hebei, China.
Changqing LiuHebei Center for Disease Control and Prevention, Shijiazhuang, Hebei, China.
Xiaoyan LuoHebei Center for Disease Control and Prevention, Shijiazhuang, Hebei, China.
Hongtong ChenDepartment of cardiothoracic Surgery, Heart Center, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lianlong YuShandong Center for Disease Control and Prevention, Ji'nan, Jinan, Shandong, China. lianlong00a@163.com.
Yao ChenPeople's Hospital of Rizhao, Rizhao, Shandong, China. spqybz@163.com.
Li YangJinan Center for Disease Control and Prevention, Jinan, Shandong, China. sduyangli2012@126.com.
Lichao ZhuDepartment of Pediatric Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. zhulichao0217@163.com.
Shandong Center for Disease Control and Prevention · CNHebei Provincial Center for Disease Control and Prevention · CNMinistry of Agriculture and Rural Affairs · CNPeople’s Hospital of Rizhao · CNQingdao University · CNShandong First Medical University · CNShandong Provincial Hospital · CNShanghai Jiao Tong University · CN

Funding

Chinese Medicine Science and Technology Project of Shandong Province Youth Project 2020Q041, 2020Q043Qilu Health Outstanding Young Talents Project NoShandong Medical and Health Science and Technology Development Project (SMHSTDP) 2019WS436Shandong Medical and Health Science and Technology Development Project (SMHSTDP), 202312050978Shandong Provincial Natural Science Foundation ZR2023QH157
6 · The paper itself

Abstract

BACKGROUND AND

objectivesTo investigate the relationship between body mass index (BMI) and blood biochemical indicators in early adolescence, and to provide ideas for early prevention of diseases and explore possible disease-related predictors.

methods3125 participants aged 10 ∼ 14 years were selected from China from the survey of "China Nutrition and Health Surveillance ( 2016 ∼ 2017 ) ". Employing advanced statistical methods, including generalized linear models, heatmaps, hierarchical clustering, and generalized additive models, the study delved into the associations between BMI and various biochemical indicators.

resultsIn early adolescence, indicators including systolic pressure, diastolic pressure, weight, height, BMI, hemoglobin, blood uric acid, serum creatinine, albumin, vitamin A presented increasing trends with the increase of age ( P < 0.05 ), whereas LDL-C, vitamin D, and ferritin showed decreasing trends with the increase of age ( P < 0.05 ). The increase in hemoglobin and blood uric acid levels with age was more pronounced in males compared to females ( P < 0.05 ). BMI was positively correlated with blood glucose, hemoglobin, triglyceride, LDL-C, blood uric acid, serum creatinine, ferritin, transferrin receptor, hs-CRP, total protein, vitamin A ( P < 0.05 ). There was a significant BMI × age interaction in the correlation analysis with LDL-C, transferrin receptor, serum creatinine, and hs-CRP ( P < 0.05 ). BMI was a risk factor for hypertension, hypertriglyceridemia, low high density lipoprotein cholesterolemia, and metabolic syndrome in all age groups ( OR > 1, P < 0.05 ).

conclusionsHigh BMI was a risk factor for hypertension, hypertriglyceridemia, low high density lipoprotein cholesterolemia, and MetS in early adolescents. With the focus on energy intake beginning in early adolescence, the maintenance of a healthy weight warrants greater attention.

Indexed as

HypertensionHypertriglyceridemiaAdolescentBody Mass IndexCholesterol, LDLC-Reactive ProteinCreatinineFemaleFerritinsHemoglobinsHumansLipoproteins, HDLMaleReceptors, TransferrinUric AcidVitamin ACholesterol, LDLC-Reactive ProteinCreatinineFerritinsHemoglobinsLipoproteins, HDLReceptors, TransferrinUric AcidVitamin AAgeBiochemical indexBlood pressureBody Mass IndexEarly adolescents

Identifiers

PMID38561702
PMCPMC10983764
OpenAlexW4393388985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.