ArticleBMC medical imaging2024
Dynamic contrast-enhanced MR imaging in identifying active anal fistula after surgery.
Article in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- A DWI histogram-based nomogram for preoperative prediction of pathogens and antibiotic resistance in perianal abscesses.International journal of colorectal disease · 2026Article
- MRI-based radiomics-deep learning model for preoperative pathogen prediction in perianal abscesses.Frontiers in medicine · 2026Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIt is challenging to identify residual or recurrent fistulas from the surgical region, while MR imaging is feasible. The aim was to use dynamic contrast-enhanced MR imaging (DCE-MRI) technology to distinguish between active anal fistula and postoperative healing (granulation) tissue.
methodsThirty-six patients following idiopathic anal fistula underwent DCE-MRI. Subjects were divided into Group I (active fistula) and Group IV (postoperative healing tissue), with the latter divided into Group II (≤ 75 days) and Group III (> 75 days) according to the 75-day interval from surgery to postoperative MRI reexamination. MRI classification and quantitative analysis were performed. Correlation between postoperative time intervals and parameters was analyzed. The difference of parameters between the four groups was analyzed, and diagnostic efficiency was tested by receiver operating characteristic curve.
resultsWash-in rate (WI) and peak enhancement intensity (PEI) were significantly higher in Group I than in Group II (p = 0.003, p = 0.040), while wash-out rate (WO), time to peak (TTP), and normalized signal intensity (NSI) were opposite (p = 0.031, p = 0.007, p = 0.010). Area under curves for discriminating active fistula from healing tissue within 75 days were 0.810 in WI, 0.708 in PEI, 0.719 in WO, 0.783 in TTP, 0.779 in NSI. All MRI parameters were significantly different between Group I and Group IV, but not between Group II and Group III, and not related to time intervals.
conclusionIn early postoperative period, DCE-MRI can be used to identify active anal fistula in the surgical area.
trial registrationChinese Clinical Trial Registry: ChiCTR2000033072.
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