Evidence map›Paper›PMID 38561590›Full record

Observational studyClinical rheumatology2024

Gardening/yardwork in people with knee osteoarthritis is not associated with symptom or structural progression over 48 months: data from the Osteoarthritis Initiative.

Grace H Lo, Julieann C Patarini, Michael J Richard, Timothy E McAlindon, Andrea M Kriska, Bonny Rockette-Wagner, Charles B Eaton, Marc C Hochberg, C Kent Kwoh, Michael C Nevitt and 1 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Grace H LoDepartment of Medicine, Baylor College of Medicine, 1 Baylor Plaza, BCM-285, Houston, TX, USA. ghlo@bcm.edu.ORCID http://orcid.org/0000-0003-3142-1839
Julieann C PatariniDivision of Rheumatology, Allergy, & Immunology, Tufts Medical Center, Boston, MA, USA.
Michael J RichardDivision of Rheumatology, Allergy, & Immunology, Tufts Medical Center, Boston, MA, USA.
Timothy E McAlindonDivision of Rheumatology, Allergy, & Immunology, Tufts Medical Center, Boston, MA, USA.
Andrea M KriskaDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.
Bonny Rockette-WagnerDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.
Charles B EatonDepartment of Family Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Marc C HochbergDepartment of Medicine and Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
C Kent KwohUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ, USA.
Michael C NevittDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Jeffrey B DribanDepartment of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Tufts Medical Center · USUniversity of Pittsburgh · USBrown University · USMichael E. DeBakey VA Medical Center · USUniversity of Arizona · USUniversity of California, San Francisco · USUniversity of Maryland, Baltimore · USUniversity of Massachusetts Chan Medical School · US

Funding

Modifiable Risk Factors for Incident and Progressive Early Knee OsteoarthritisK23AR062127 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI LO, GRACE · 2012 to 2016
$676k
NIAMS NIH HHS K23 AR062127
6 · The paper itself

Abstract

objectiveTo evaluate the relationship of gardening/yardwork with symptomatic and structural progression in those with pre-existing radiographic knee osteoarthritis (OA) in the Osteoarthritis Initiative (OAI), an observational study designed to evaluate potential and known biomarkers and risk factors of knee OA.

methodsWe conducted a cohort study nested within the OAI, including participants ≥ 50 years old with radiographic OA in at least one knee at the time of OAI enrollment. A participant reported the level of gardening/yardwork activity in a self-administered survey. Logistic regression analyses were used to evaluate the association of gardening/yardwork on new frequent knee pain, Kellgren-Lawrence (KL) worsening, medial joint space narrowing (JSN) worsening, and improved frequent knee pain.

resultsOf 1808 knees (1203 participants), over 60% of knees had KL grade = 2, 65% had medial JSN, and slightly more than a third had frequent knee symptoms. Gardeners/yardworkers and non-gardners/yardworkers had similar "worsening" outcomes for new knee pain (29% vs. 29%), KL worsening (19% vs. 18%), and medial JSN (23% vs. 24%). The adjusted odds ratio (OR) for the "worsening" outcomes of new knee pain, KL worsening, and medial JSN worsening were 1.0 (0.7-1.3), 1.0 (0.8-1.3), and 1.1 (0.9-1.4), respectively. The gardeners/yardworkers had an adjusted OR of 1.2 (0.9-1.7) for improved knee pain compared with non-gardners/yardworkers.

conclusionGardening/yardwork is not associated with knee OA progression and should not be discouraged in those with knee OA. Key Points • Gardening/yardwork is not associated with knee OA symptomatic or structural progression. • Gardening/yardwork should not be discouraged in people with knee OA.

Indexed as

Osteoarthritis, KneeCohort StudiesDisease ProgressionGardeningHumansKnee JointMiddle AgedPainEpidemiologyGardeningKneeObservational studiesOsteoarthritis

Identifiers

PMID38561590
OpenAlexW4393378606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.