Evidence map›Paper›PMID 38561526›Full record

ArticleEuropean radiology experimental2024

Diffusion tensor imaging in anisotropic tissues: application of reduced gradient vector schemes in peripheral nerves.

Olivia Foesleitner, Alba Sulaj, Volker Sturm, Moritz Kronlage, Fabian Preisner, Zoltan Kender, Martin Bendszus, Julia Szendroedi, Sabine Heiland, Daniel Schwarz

Open access · goldAbstract read
In one paragraph

Article in European radiology experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Olivia FoesleitnerDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Alba SulajDepartment of Internal Medicine I and Clinical Chemistry, Heidelberg University Hospital, INF 410, Heidelberg, Germany.
Volker SturmDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Moritz KronlageDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Fabian PreisnerDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Zoltan KenderDepartment of Internal Medicine I and Clinical Chemistry, Heidelberg University Hospital, INF 410, Heidelberg, Germany.
Martin BendszusDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Julia SzendroediDepartment of Internal Medicine I and Clinical Chemistry, Heidelberg University Hospital, INF 410, Heidelberg, Germany.
Sabine HeilandDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
Daniel SchwarzDepartment of Neuroradiology, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany. daniel.schwarz@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0002-9017-8245
Heidelberg University · DE

Funding

Deutsche Forschungsgemeinschaft SFB 1118Deutsche Forschungsgemeinschaft SFB 1158
6 · The paper itself

Abstract

backgroundIn contrast to the brain, fibers within peripheral nerves have distinct monodirectional structure questioning the necessity of complex multidirectional gradient vector schemes for DTI. This proof-of-concept study investigated the diagnostic utility of reduced gradient vector schemes in peripheral nerve DTI.

methodsThree-Tesla magnetic resonance neurography of the tibial nerve using 20-vector DTI (DTI

resultsSimplified datasets achieved excellent diagnostic accuracy equal to DTI

conclusionsIn peripheral nerves, bulk tissue DTI metrics can be approximated with only three predefined gradient vectors along the scanner's main axes, yielding similar diagnostic accuracy as a 20-vector DTI, resulting in substantial scan time reduction. RELEVANCE STATEMENT: DTI bulk tissue parameters of peripheral nerves can be calculated with only three predefined gradient vectors at similar diagnostic performance as a standard DTI but providing a substantial scan time reduction. KEY POINTS: • In peripheral nerves, DTI parameters can be approximated using only three gradient vectors. • The simplified model achieves a similar diagnostic performance as a standard DTI. • The simplified model allows for a significant acceleration of image acquisition. • This can help to introduce multi-b-value DTI techniques into clinical practice.

Indexed as

Diabetes Mellitus, Type 2Diffusion Tensor ImagingAnisotropyDiffusion Magnetic Resonance ImagingHumansPeripheral NervesDiabetes mellitus (type 2)Diffusion tensor imagingHealthy volunteersMagnetic resonance imagingPeripheral nerves

Identifiers

PMID38561526
PMCPMC10984907
OpenAlexW4393375958

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.