Evidence map›Paper›PMID 38561223›Full record

ArticleLife science alliance2024

Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome.

Valerie S LeBleu, Keizo Kanasaki, Sara Lovisa, Joseph L Alge, Jiha Kim, Yang Chen, Yingqi Teng, Behzad Gerami-Naini, Hikaru Sugimoto, Noritoshi Kato and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Cell Fusion in Reprogramming and Regeneration.Advances in experimental medicine and biology · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 2 countries.

Valerie S LeBleuDepartment of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA Valerie.lebleu@bcm.edu.ORCID 0000-0002-8514-8551
Keizo KanasakiDivision of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Sara LovisaDepartment of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-7776-2896
Joseph L AlgeDepartment of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jiha KimDepartment of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yang ChenDepartment of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yingqi TengDivision of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Behzad Gerami-NainiDivision of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Hikaru SugimotoDepartment of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Noritoshi KatoDivision of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-3924-6887
Ignacio RevueltaDivision of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-3584-4516
Nicole GrauMedical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
Jonathan P SleemanMedical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.ORCID 0000-0003-1718-7687
Gangadhar TaduriDivision of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Akane KizuDivision of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Shahin RafiiDepartment of Genetic Medicine and Ansary Stem Cell Institute, Weill Cornell Medical College, New York, NY, USA.
Konrad HochedlingerMassachusetts General Hospital, Boston, MA, USA.
Susan E QuagginNorthwestern University Feinberg School of Medicine & Feinberg Cardiovascular and Renal Research Institute, Chicago, IL, USA.
Raghu KalluriDepartment of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA rkalluri@mdanderson.org.ORCID 0000-0002-2190-547X
Beth Israel Deaconess Medical Center · USThe University of Texas MD Anderson Cancer Center · USNorthwestern University · USCornell University · USHeidelberg University · DEKarlsruhe Institute of Technology · DEMassachusetts General Hospital · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Training Program in Cardiovascular ResearchT32HL007374 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MITTLEMAN, MURRAY A · 1985 to 2019
$7.9M
Resource Development CoreU54DK137516 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Evan Alexander Scott · 2023 to 2026
$4.8M
RESEARCH TRAINING IN GASTROENTEROLOGYT32DK007760 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KELLY, CIARAN P · 1999 to 2019
$4.6M
TYPE IV COLLAGEN IN ALPORT SYNDROME PATHOGENESISR01DK055001 · NIDDK · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KALLURI, RAGHU · 1999 to 2014
$4.3M
NCI NIH HHS P30 CA016672NHLBI NIH HHS T32 HL007374NIDDK NIH HHS R01 DK055001NIDDK NIH HHS T32 DK007760NIDDK NIH HHS U54 DK137516
6 · The paper itself

Abstract

Glomerular filtration relies on the type IV collagen (ColIV) network of the glomerular basement membrane, namely, in the triple helical molecules containing the α3, α4, and α5 chains of ColIV. Loss of function mutations in the genes encoding these chains (

Indexed as

Nephritis, HereditaryPodocytesAnimalsCollagen Type IVGlomerular Basement MembraneMiceStem CellsCollagen Type IV

Identifiers

PMID38561223
PMCPMC10985218
OpenAlexW4393373665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.