Evidence map›Paper›PMID 38561180›Full record

ArticleBioinformatics (Oxford, England)2024

POCP-nf: an automatic Nextflow pipeline for calculating the percentage of conserved proteins in bacterial taxonomy.

Martin Hölzer

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Novel Thermophilic Species ofLife (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. International journal of systematic and evolutionary microbiology · 2026
    Article
  5. Physiology, functional genomics, and proteomics ofApplied and environmental microbiology · 2026
    Article
  6. International journal of systematic and evolutionary microbiology · 2026
    Article
  7. Article
  8. Article
  9. Taxonomic description of a novel genus,International journal of systematic and evolutionary microbiology · 2026
    Article
  10. Article
  11. Draft metagenome-assembled genome sequence of aMicrobiology resource announcements · 2026
    Article
  12. International journal of systematic and evolutionary microbiology · 2026
    Article
  13. ThreeViruses · 2026
    Article
  14. Article
  15. Current research in microbial sciences · 2026
    Article
  16. Resolving taxonomic uncertainties in the genusFrontiers in microbiology · 2026
    Article
  17. Reclassification of the genusInternational journal of systematic and evolutionary microbiology · 2026
    Article
  18. Microbial Evolution and Systematics: Archaea and Bacteria.Progress in molecular and subcellular biology · 2026
    Review
  19. International journal of molecular sciences · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Martin HölzerGenome Competence Center (MF1), Robert Koch Institute, 13353 Berlin, Germany.ORCID 0000-0001-7090-8717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summarySequence technology advancements have led to an exponential increase in bacterial genomes, necessitating robust taxonomic classification methods. The Percentage Of Conserved Proteins (POCP), proposed initially by Qin et al. (2014), is a valuable metric for assessing prokaryote genus boundaries. Here, I introduce a computational pipeline for automated POCP calculation, aiming to enhance reproducibility and ease of use in taxonomic studies. AVAILABILITY AND IMPLEMENTATION: The POCP-nf pipeline uses DIAMOND for faster protein alignments, achieving similar sensitivity to BLASTP. The pipeline is implemented in Nextflow with Conda and Docker support and is freely available on GitHub under https://github.com/hoelzer/pocp. The open-source code can be easily adapted for various prokaryotic genome and protein datasets. Detailed documentation and usage instructions are provided in the repository.

Indexed as

Prokaryotic CellsSoftwareGenome, BacterialReproducibility of Results

Identifiers

PMID38561180
PMCPMC11256958

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.