Evidence map›Paper›PMID 38561049›Full record

Observational studyThe Journal of pediatrics2024

Predicting Extubation Readiness in Preterm Infants Utilizing Machine Learning: A Diagnostic Utility Study.

Mandy Brasher, Alexandr Virodov, Thomas M Raffay, Henrietta S Bada, M Douglas Cunningham, Cody Bumgardner, Elie G Abu Jawdeh

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The Journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. The effect of postnatal steroids on lung ultrasound scores and extubation readiness in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mandy BrasherDepartment of Pediatrics/Neonatology, College of Medicine, University of Kentucky, Lexington, KY.
Alexandr VirodovInstitute of Biomedical Informatics, University of Kentucky, Lexington, KY.
Thomas M RaffayDepartment of Pediatrics/Neonatology, College of Medicine, Case Western Reserve University, Cleveland, OH.
Henrietta S BadaDepartment of Pediatrics/Neonatology, College of Medicine, University of Kentucky, Lexington, KY.
M Douglas CunninghamDepartment of Pediatrics/Neonatology, College of Medicine, University of Kentucky, Lexington, KY.
Cody BumgardnerInstitute of Biomedical Informatics, University of Kentucky, Lexington, KY.
Elie G Abu JawdehDepartment of Pediatrics/Neonatology, College of Medicine, University of Kentucky, Lexington, KY. Electronic address: elie.abujawdeh@uky.edu.
University of Kentucky · USCase Western Reserve University · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Systemic Mediators and Biomarkers of Injury in Preterm Infants with Intermittent HypoxemiaK23HD109471 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI Elie G Abu Jawdeh · 2023 to 2026
$644k
NCATS NIH HHS UL1 TR001998NICHD NIH HHS K23 HD109471
6 · The paper itself

Abstract

objectiveThe objective of this study was to predict extubation readiness in preterm infants using machine learning analysis of bedside pulse oximeter and ventilator data. STUDY

designThis is an observational study with prospective recordings of oxygen saturation (SpO

resultsA total of 110 extubation events from 110 preterm infants were analyzed. Infants had a median gestation age and birth weight of 26 weeks and 825 g, respectively. Of the 3 models presented, the IH + SIMV model achieved the highest AUC of 0.77 for all infants. Separating infants by postnatal age increased accuracy further achieving AUC of 0.94 for <2 weeks of age group and AUC of 0.83 for ≥2 weeks group.

conclusionsMachine learning analysis has the potential to enhance prediction accuracy of extubation readiness in preterm infants while utilizing readily available data streams from bedside pulse oximeters and ventilators.

Indexed as

Airway ExtubationInfant, PrematureMachine LearningOximetryFemaleGestational AgeHumansHypoxiaInfant, NewbornMaleOxygen SaturationProspective StudiesROC CurveVentilator Weaningbedside monitoringextubation attemptextubation failureextubation successmechanical ventilationneonatal intensive careprediction toolpreterm infants

Identifiers

PMID38561049
PMCPMC12055302
OpenAlexW4393346256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.