ArticleBJA open2024
The role of methadone in cardiac surgery for management of postoperative pain.
Article in BJA open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Efficacy and safety of intravenous methadone for pain management in cardiac surgery: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Intravenous methadone for pain management in cardiac surgery: a randomised controlled trial with plasma concentration analysis.Anaesthesia · 2026Trial
- Single-dose intraoperative methadone and QTc interval: a prospective observational cohort investigation.British journal of anaesthesia · 2026Observational
- Improving postoperative pain management after minimally invasive coronary surgery using methadone analgesia and early chest drain removal.Journal of thoracic disease · 2026Article
- Analgesia for Thoracic Surgery: Does Intraoperative Methadone Deserve a Place?ANZ journal of surgery · 2025Article
- Perioperative Considerations, Anesthetic Management and Transesophageal Echocardiographic Evaluation of Patients Undergoing the Ross Procedure.Journal of cardiovascular development and disease · 2025Review
- Enhanced Recovery After Surgery (ERAS) Protocols in Cardiac Surgery: Impact on Opioid Consumption.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This retrospective study evaluated the efficacy and safety of intraoperative methadone compared with short-acting opioids. Methods: Patients undergoing cardiac surgery with cardiopulmonary bypass ( Results: Patients in Groups M and M+O had lower mean pain scores until postoperative day (POD) 7 compared with Group O after adjusting for covariates ( Conclusions: Intraoperative administration of methadone was associated with better pain control without significant side-effects after cardiac surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.