ArticleOpen forum infectious diseases2024
Epidemiology, Timing, and Secondary Prophylaxis of Recurrent Nocardiosis.
Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Imaging characteristics, yield of computed tomography, and clinical outcomes of central nervous system nocardiosis.Infection · 2026Article
- Bacterial Granulomatous Lung Diseases: Radiological Findings and Differential Diagnosis.Infectious disease reports · 2026Review
- A 56-Year-Old Woman With Systemic Lupus Erythematosus on Trimethoprim-Sulfamethoxazole Prophylaxis Presenting With Breakthrough Nocardiosis.The American journal of case reports · 2026Article
- A landscape of epidemiology and strain distribution ofBiosafety and health · 2026Article
- Persistent CD4Frontiers in immunology · 2026Article
- Nocardia Isolation in People with Cystic Fibrosis and Non-CF Bronchiectasis: A Multicenter Italian Study.Antibiotics (Basel, Switzerland) · 2025Article
- Musculoskeletal infections associated withJournal of bone and joint infection · 2024Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Background: Methods: We performed a multicenter, retrospective cohort study of adults diagnosed with nocardiosis from November 2011 to April 2022, including patients who completed primary treatment and had at least 30 days of posttreatment follow-up. Propensity score matching was used to analyze the effect of secondary prophylaxis on Results: Fifteen of 303 (5.0%) patients developed recurrent nocardiosis after primary treatment. Most recurrences were diagnosed either within 60 days (N = 6/15, 40.0%) or between 2 to 3 years (N = 4/15, 26.7%). Patients with primary disseminated infection tended to recur within 1 year, whereas later recurrences were often nondisseminated pulmonary infection. Seventy-eight (25.7%) patients were prescribed secondary prophylaxis, mostly trimethoprim-sulfamethoxazole (N = 67/78). After propensity-matching, secondary prophylaxis was not associated with reduced risk of recurrence (hazard ratio, 0.96; 95% confidence interval, .24-3.83), including in multiple subgroups. Eight (53.3%) patients with recurrent nocardiosis required hospitalization and no patients died from recurrent infection. Conclusions: Recurrent nocardiosis tends to occur either within months because of the same
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.