Evidence map›Paper›PMID 38560550›Full record

ArticleTobacco induced diseases2024

Investigation of the impact of thirdhand e-cigarette exposure on platelet function: A pre-clinical study.

Shelby S Umphres, Ahmed B Alarabi, Hamdy E A Ali, Fadi T Khasawneh, Fatima Z Alshbool

Open access · goldAbstract read
In one paragraph

Article in Tobacco induced diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. The Effects of Thirdhand Vape Residue from Nicotine and Non-Nicotine Vapes on Cells: A Systematic Review.International journal of environmental research and public health · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Shelby S UmphresDepartment of Pharmaceutical Sciences, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Kingsville, United States.
Ahmed B AlarabiDepartment of Pharmaceutical Sciences, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Kingsville, United States.
Hamdy E A AliDepartment of Pharmaceutical Sciences, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Kingsville, United States.
Fadi T KhasawnehDepartment of Pharmaceutical Sciences, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Kingsville, United States.
Fatima Z AlshboolDepartment of Pharmacy Practice, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Kingsville, United States.
Texas A&M University – Kingsville · US

Funding

The Mechanistic Impact of Paternal Electronic Nicotine Delivery Systems Exposure on ThrombogenesisR01HL145053 · NHLBI · UNIVERSITY OF TEXAS EL PASO · PI Fadi T Khasawneh · 2019 to 2026
$3.6M
Investigate the mechanism and impact of E-cigarettes on platelet function and thrombogenesisR56HL158730 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALSHBOOL, FATIMA Z. · 2022 to 2022
$535k
The Effects of Prenatal Thirdhand E-cigarette Exposure on PlateletsR21ES034512 · NIEHS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI KHASAWNEH, FADI T · 2022 to 2023
$483k
The Impact of In Utero E-Cigarette Exposure on Platelet Function and ThrombogenesisR21HD105187 · NICHD · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALSHBOOL, FATIMA Z. · 2022 to 2023
$417k
In Utero Third-Hand Smoke Impact on Platelet Function and ThrombogenesisR21ES029345 · NIEHS · UNIVERSITY OF TEXAS EL PASO · PI KHASAWNEH, FADI T · 2018 to 2020
$416k
The Impact of Third-Hand E#Cigarette Exposure on Platelet Function and ThrombogenesisR03ES030486 · NIEHS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALSHBOOL, FATIMA Z. · 2020 to 2021
$152k
NHLBI NIH HHS R01 HL145053NHLBI NIH HHS R56 HL158730NICHD NIH HHS R21 HD105187NIEHS NIH HHS R03 ES030486NIEHS NIH HHS R21 ES029345NIEHS NIH HHS R21 ES034512
6 · The paper itself

Abstract

introductionThe use of e-cigarettes (ECs) has reached unprecedented levels, due to a variety of reasons, including the misconception regarding their safety. Thus, there have been efforts to characterize the effects of EC exposure, including in the context of thirdhand EC (THEC) on a host of disorders, such as cardiovascular disease (CVD).

methodsTo address this issue, we sought to characterize the effects of THEC on platelet function and thrombus formation, using a novel mouse exposure protocol that resembles real life scenarios. To assess these effects, a host of related

resultsOur

conclusionsTaken together, these results provide evidence that THEC does have the capacity to increase the risk of thrombotic disease, which should increase awareness regarding its underappreciated negative health effects.

Indexed as

cardiovascular diseasee-cigaretteplateletthirdhand tobacco exposurethrombosis

Identifiers

PMID38560550
PMCPMC10980912
OpenAlexW4393334005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.