Evidence map›Paper›PMID 38560417›Full record

ArticleAmerican heart journal plus : cardiology research and practice2022

Mortality and length of stay among HIV patients hospitalized for heart failure: A multicenter retrospective study.

Jonathan Brown, Aswin Srinivasan, Hytham Rashid, Brendon Cornett, Syed Raza, Zuhair Ali

Open access · goldAbstract read
In one paragraph

Article in American heart journal plus : cardiology research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jonathan BrownDepartment of Internal Medicine, HCA Kingwood/University of Houston College of Medicine, Kingwood, TX, United States of America.
Aswin SrinivasanDepartment of Internal Medicine, HCA Kingwood/University of Houston College of Medicine, Kingwood, TX, United States of America.
Hytham RashidDepartment of Internal Medicine, HCA Kingwood/University of Houston College of Medicine, Kingwood, TX, United States of America.
Brendon CornettDepartment of Graduate Medical Education, HCA Healthcare, Brentwood, TN, United States of America.
Syed RazaDepartment of Cardiology, HCA Kingwood/University of Houston College of Medicine, Kingwood, TX, United States of America.
Zuhair AliDepartment of Internal Medicine, HCA Kingwood/University of Houston College of Medicine, Kingwood, TX, United States of America.
Lone Star College Kingwood · USUniversity of Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study objective: The purpose of our study was to determine if CD4+ T-lymphocyte count (CD4 count) was inversely associated with inpatient mortality and length of stay (LOS) among patients with HIV hospitalized for acute heart failure. Design: Retrospective cohort study. Setting: HCA hospitals throughout the United States. Participants: 1704 patients with human immunodeficiency virus (HIV) hospitalized for acute heart failure with a documented, time-updated CD4 count. Interventions: Patients were categorized by CD4 count ranges consisting of >500, 200-499, <200 cells/μL. Main outcome measures: A multivariable negative binomial regression was performed with CD4 count as a predictor of length of stay. Multivariable logistic regression was performed with CD4 count as a predictor of mortality. Results: A CD4 count <200 cells/μL was associated with an increased length of stay compared to a CD4 > 500 cells/μL (IRR 1.24, 95 % CI: 1.11 to 1.39, P ≤ 0.01). A CD4 of 200-499 cells/μL was associated with a shorter LOS compared to a CD4 < 200 cells/μL (IRR 0.82, 95 % CI: 0.75 to 0.89, P ≤ 0.01). A CD4 < 200 cells/μL was associated with an increased mortality compared to a CD4 > 500 cells/μL (OR 3.62, 95 % CI: 1.63 to 8.05, P ≤ 0.01). CD4 count was not independently associated with in-patient mortality after adjusting for viral load. Conclusion: A time-updated CD4 count <200 cells/μL on hospital admission was independently associated with increased length of stay. CD4 cell count and viral load are important markers when considering the morbidity and mortality among patients with HIV hospitalized for acute heart failure.

Indexed as

Acute heart failureHuman immunodeficiency virusIn-hospital mortalityLength of stay

Identifiers

PMID38560417
PMCPMC10978338
OpenAlexW4291173013

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.