Evidence map›Paper›PMID 38560374›Full record

ArticleHeart rhythm O22024

Left bundle branch pacing vs ventricular septal pacing for cardiac resynchronization therapy.

Jingjing Chen, Fatima M Ezzeddine, Xiaoke Liu, Vaibhav Vaidya, Christopher J McLeod, Arturo M Valverde, Freddy Del-Carpio Munoz, Abhishek J Deshmukh, Malini Madhavan, Ammar M Killu and 3 more

Abstract read
In one paragraph

Article in Heart rhythm O2, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Improved outcomes of left bundle branch pacing compared to left ventricular septal pacing in patients with heart failure: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Left bundle branch pacing in patients with structural heart disease: personalizing cardiac resynchronization therapy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Review
  8. Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jingjing ChenDepartment of Cardiovascular Medicine, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Fatima M EzzeddineDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Xiaoke LiuDepartment of Cardiovascular Medicine, Mayo Clinic, La Crosse, Wisconsin.
Vaibhav VaidyaDepartment of Cardiovascular Medicine, Mayo Clinic, Eau Claire, Wisconsin.
Christopher J McLeodDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
Arturo M ValverdeDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, Arizona.
Freddy Del-Carpio MunozDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Abhishek J DeshmukhDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Malini MadhavanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Ammar M KilluDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Siva K MulpuruDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Paul A FriedmanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Yong-Mei ChaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The outcomes of left bundle branch pacing (LBBP) and left ventricular septal pacing (LVSP) in patients with heart failure remain to be learned. Objective: The objective of this study was to assess the echocardiographic and clinical outcomes of LBBP, LVSP, and deep septal pacing (DSP). Methods: This retrospective study included patients who met the criteria for cardiac resynchronization therapy (CRT) and underwent attempted LBBP in 5 Mayo centers. Clinical, electrocardiographic, and echocardiographic data were collected at baseline and follow-up. Results: A total of 91 consecutive patients were included in the study. A total of 52 patients had LBBP, 25 had LVSP, and 14 had DSP. The median follow-up duration was 307 (interquartile range 208, 508) days. There was significant left ventricular ejection fraction (LVEF) improvement in the LBBP and LVSP groups (from 35.9 ± 8.5% to 46.9 ± 10.0%, Conclusion: In patients undergoing CRT, LVSP had comparable CRT outcomes compared with LBBP.

Indexed as

Cardiac resynchronization therapyDeep septal pacingHeart failureLeft bundle branch pacingLeft ventricular septal pacing

Identifiers

PMID38560374
PMCPMC10980924

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.