Evidence map›Paper›PMID 38560323›Full record

ArticleJournal of orthopaedic case reports2024

Culture Negative Pasteurella multocida Confirmed Prosthetic Hip Infection using Next-generation Sequencing.

Henry Kuechly, Rajul Gupta, Sarah Kurkowski, Zachary Crawford, Toan Le

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of orthopaedic case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Genetic applications in arthroplasty: A review.Bulletin of the Hospital for Joint Disease (2013) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Henry KuechlyDepartment of Orthopedic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Rajul GuptaDepartment of Orthopedic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Sarah KurkowskiDepartment of Orthopedic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Zachary CrawfordDepartment of Orthopedic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Toan LeDepartment of Orthopedic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio.
University of Cincinnati Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Prosthetic joint infections (PJIs) are a dreaded complication of joint arthroplasty. Zoonotic organisms such as Pasteurella multocida (PM) rarely cause PJIs. Still, these organisms can be challenging to treat due to a low suspicion index and inadequate growth on culture. Next-generation sequencing (NGS) can be used to identify organisms in culture-negative PJIs. This is the first reported case of a PM positive total hip arthroplasty PJI using NGS. Case Report: We report the case of a 70-year-old male presenting with a periprosthetic hip infection. PM was identified in high relative abundance on NGS and grew in culture. Subsequent intraoperative samples were culture negative for Pasteurella, but NGS demonstrated continued presence of Pasteurella. Conclusion: PM is a rare case of PJI, but a high index of suspicion must be maintained in the appropriate clinical context. NGS is a vital tool for the identification of culture-negative organisms like PM.

Indexed as

arthroplastyhip infectionnext-generation sequencingnext-generation sequencing×culture negativePasteurella multocidaProsthetic joint infection

Identifiers

PMID38560323
PMCPMC10976524
OpenAlexW4393005780

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.