Evidence map›Paper›PMID 38559981›Full record

ArticleACS omega2024

FZD7-Targeted Nanoparticles to Enhance Doxorubicin Treatment of Triple-Negative Breast Cancer.

Elise C Hoover, Olivia M Ruggiero, Rachel N Swingler, Emily S Day

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Functionalized Nanomaterials in Cancer Treatment: A Review.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elise C HooverDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware 19713, United States.ORCID https://orcid.org/0000-0003-4723-7446
Olivia M RuggieroDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware 19713, United States.
Rachel N SwinglerDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware 19713, United States.
Emily S DayDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware 19713, United States.ORCID https://orcid.org/0000-0002-8707-826X
University of Delaware · US

Funding

Multifunctional siRNA/antibody nanocarriers to treat metastatic triple-negative breast cancerR01CA211925 · NCI · UNIVERSITY OF DELAWARE · PI DAY, EMILY S · 2019 to 2023
$1.7M
NCI NIH HHS R01 CA211925
6 · The paper itself

Abstract

Doxorubicin (DOX) is a chemotherapy agent commonly used to treat triple-negative breast cancer (TNBC), but it has insufficient efficacy against the disease and considerable toxicity due to its off-target delivery. To improve the specificity of DOX for TNBC, we encapsulated it in poly(lactic-

Identifiers

PMID38559981
PMCPMC10976388
OpenAlexW4392878378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.