Evidence map›Paper›PMID 38559770›Full record

ArticleEnvironmental epigenetics2024

Exposure to air pollution is associated with DNA methylation changes in sperm.

Rose Schrott, Jason I Feinberg, Craig J Newschaffer, Irva Hertz-Picciotto, Lisa A Croen, M Daniele Fallin, Heather E Volk, Christine Ladd-Acosta, Andrew P Feinberg

Open access · goldAbstract read
In one paragraph

Article in Environmental epigenetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Rose SchrottWendy Klag Center for Autism and Developmental Disabilities, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID https://orcid.org/0000-0001-8224-9245
Jason I FeinbergWendy Klag Center for Autism and Developmental Disabilities, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Craig J NewschafferDepartment of Biobehavioral Health, College of Health and Human Development, Pennsylvania State University, State College, PA 16802, USA.
Irva Hertz-PicciottoDepartment of Public Health Sciences, MIND (Medical Investigations of Neurodevelopmental Disorders) Institute, University of California, Davis, CA 95616, USA.
Lisa A CroenDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
M Daniele FallinRollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
Heather E VolkWendy Klag Center for Autism and Developmental Disabilities, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Christine Ladd-AcostaWendy Klag Center for Autism and Developmental Disabilities, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Andrew P FeinbergDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Johns Hopkins University · USEmory University · USKaiser Permanente · USPennsylvania State University · USUniversity of California Davis Medical Center · US

Funding

Expanding the Value of the EARLI study: Small Cohort with Big DataR24ES030893 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI VOLK, HEATHER E · 2020 to 2024
$2.0M
NIEHS NIH HHS R24 ES030893
6 · The paper itself

Abstract

Exposure to air pollutants has been associated with adverse health outcomes in adults and children who were prenatally exposed. In addition to reducing exposure to air pollutants, it is important to identify their biologic targets in order to mitigate the health consequences of exposure. One molecular change associated with prenatal exposure to air pollutants is DNA methylation (DNAm), which has been associated with changes in placenta and cord blood tissues at birth. However, little is known about how air pollution exposure impacts the sperm epigenome, which could provide important insights into the mechanism of transmission to offspring. In the present study, we explored whether exposure to particulate matter less than 2.5 microns in diameter, particulate matter less than 10 microns in diameter, nitrogen dioxide (NO

Indexed as

air pollutionDNA methylationepigeneticsgenome-scalesperm

Identifiers

PMID38559770
PMCPMC10980975
OpenAlexW4391684175

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.