Evidence map›Paper›PMID 38559622›Full record

ArticleJACC. Basic to translational science2024

Follicle-Stimulating Hormone Exacerbates Cardiovascular Disease in the Presence of Low or Castrate Testosterone Levels.

Wilhelmina C M Duivenvoorden, David Margel, Vishal Subramony Gayathri, Emmanuelle Duceppe, Sadiya Yousef, Magda Naeim, Mohammad Khajehei, Sarah Hopmans, Snezana Popovic, Yaara Ber and 3 more

Open access · goldAbstract read
In one paragraph

Article in JACC. Basic to translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Cardiovascular risk in ADT recipients: does the type of ADT matter?Prostate cancer and prostatic diseases · 2024
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Wilhelmina C M DuivenvoordenDepartment of Surgery, Division of Urology, Faculty of Medicine, McMaster University, Hamilton, Ontario, Canada.
David MargelDepartment of Urology, Rabin Medical Center, Petach Tikva, Israel.
Vishal Subramony GayathriResearch Institute of St. Joe's Hamilton, Hamilton, Ontario, Canada.
Emmanuelle DuceppePopulation Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.
Sadiya YousefResearch Institute of St. Joe's Hamilton, Hamilton, Ontario, Canada.
Magda NaeimResearch Institute of St. Joe's Hamilton, Hamilton, Ontario, Canada.
Mohammad KhajeheiDepartment of Surgery, Division of Urology, Faculty of Medicine, McMaster University, Hamilton, Ontario, Canada.
Sarah HopmansDepartment of Surgery, Division of Urology, Faculty of Medicine, McMaster University, Hamilton, Ontario, Canada.
Snezana PopovicDepartment of Pathology and Molecular Medicine, Faculty of Medicine, McMaster University, Hamilton, Ontario, Canada.
Yaara BerDepartment of Urology, Rabin Medical Center, Petach Tikva, Israel.
Diane Heels-AnsdellDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Philip J DevereauxPopulation Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.
Jehonathan H PinthusDepartment of Surgery, Division of Urology, Faculty of Medicine, McMaster University, Hamilton, Ontario, Canada.
St. Joseph’s Healthcare Hamilton · CAMcMaster University · CACentre Hospitalier de l’Université de Montréal · CAImpact · CARabin Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low testosterone (T), common in aging men, associates with cardiovascular disease. We investigated whether follicle-stimulating hormone (FSH), which is affected by T, modulates the cardiovascular effects associated with low T or castration. FSHβ

Indexed as

androgen-deprivation therapycardiovascular diseasefollicle-stimulating hormoneGnRH-antagonistprostate cancer

Identifiers

PMID38559622
PMCPMC10978407
OpenAlexW4389997018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.