Evidence map›Paper›PMID 38559493›Full record

ArticleThe World Allergy Organization journal2024

The mental health burden of food allergies: Insights from patients and their caregivers from the Food Allergy Research & Education (FARE) Patient Registry.

Thomas B Casale, Christopher Warren, Sachin Gupta, Robert Schuldt, Rongrong Wang, Ahmar Iqbal, Arpamas Seetasith, Ruchi Gupta

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04653324 (The FARE Patient Registry), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04653324 recruitingnot on this map

The FARE Patient Registry: A Registry for the Food Allergy Community

Typeobservational_patient_registrySponsorFood Allergy Research & EducationRan2017 to 2027Enrolled23,000ConditionsFood Hypersensitivity, Anaphylaxis, Eosinophilic Esophagitis, Food Sensitivity
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Confronting fear and uncertainty: adults' experiences of undergoing a food challenge test for food allergy.International journal of qualitative studies on health and well-being · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Food allergy-related bullying in children: Prevalence and psychosocial burden from a mixed-methods study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Observational
  11. Review
  12. Article
  13. Article
  14. The hidden price of food allergy: Understanding the social and financial burdens on families.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Thomas B CasaleDivision of Allergy and Immunology, University of South Florida, Tampa, FL, USA.
Christopher WarrenNorthwestern University, Chicago, IL, USA.
Sachin GuptaGenentech, Inc., South San Francisco, CA, USA.
Robert SchuldtGenentech, Inc., South San Francisco, CA, USA.
Rongrong WangGenentech, Inc., South San Francisco, CA, USA.
Ahmar IqbalGenentech, Inc., South San Francisco, CA, USA.
Arpamas SeetasithGenentech, Inc., South San Francisco, CA, USA.
Ruchi GuptaNorthwestern University, Chicago, IL, USA.
Northwestern University · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Food allergies impose a large psychosocial burden, including mental, emotional, and social aspects, on both patients and their caregivers. Patients, caregivers, and their families often experience anxiety, isolation, and fear around food allergies. Objective: To assess the real-world mental health burden of food allergies, using the Food Allergy Research & Education (FARE) Patient Registry (NCT04653324). Methods: Self-reported data from patients with food allergies, and their caregivers, were analyzed from the FARE Food Allergy History and Mental Health Concerns surveys. Odds ratios were also calculated as a measure of association between patient food allergy characteristics and the likelihood of having mental health concerns or a formal mental health diagnosis. Results: The FARE Patient Registry included 1680 patients/caregivers. Anxiety (54%) and panic (32%) were the most common emotions that patients reported as a result of eating the food that produced an allergic reaction. About two-thirds of patients reported mental health concerns related to food allergies (62%), including anxiety after an allergic reaction, anxiety about living with food allergies, and concerns about food avoidance. Caregivers also experienced fear for the safety of their children, and often sought mental health care to cope with worry related to caring for patients with food allergies. The likelihood of having food allergy-related mental health concerns was increased for patients experiencing more than 1 reaction per year (OR 1.68-1.90) and was lowered for patients having a formal mental health diagnosis (OR 0.43). Caregivers filling out the FARE survey for pediatric patients (OR 4.03) and experiencing food allergy-related mental health concerns (OR 2.36) were both significant predictors for having a formal mental health diagnosis. Conclusion: Our study highlights a continuing unmet need for mental health screening and support as part of the management of patients with food allergies.

Indexed as

AnaphylaxisAnxietyCaregiversFood allergyFood hypersensitivityMental health

Identifiers

PMID38559493
PMCPMC10973659
OpenAlexW4393116533

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.