Evidence map›Paper›PMID 38559298›Full record

ArticleACS central science2024

A Sample-Centric and Knowledge-Driven Computational Framework for Natural Products Drug Discovery.

Arnaud Gaudry, Marco Pagni, Florence Mehl, Sébastien Moretti, Luis-Manuel Quiros-Guerrero, Luca Cappelletti, Adriano Rutz, Marcel Kaiser, Laurence Marcourt, Emerson Ferreira Queiroz and 5 more

Abstract readNews
In one paragraph

Article in ACS central science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Arnaud GaudryInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva 4, Switzerland.ORCID https://orcid.org/0000-0002-3648-7362
Marco PagniVital-IT, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.ORCID https://orcid.org/0000-0001-9292-9463
Florence MehlVital-IT, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-9619-1707
Sébastien MorettiVital-IT, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.ORCID https://orcid.org/0000-0003-3947-488X
Luis-Manuel Quiros-GuerreroInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva 4, Switzerland.ORCID https://orcid.org/0000-0002-1630-8697
Luca CappellettiDepartment of Biology, University of Fribourg, 1700 Fribourg, Switzerland.ORCID https://orcid.org/0000-0002-1269-2038
Adriano RutzInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva 4, Switzerland.ORCID https://orcid.org/0000-0003-0443-9902
Marcel KaiserDepartment of Medical and Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland.
Laurence MarcourtInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva 4, Switzerland.ORCID https://orcid.org/0000-0002-9614-1099
Emerson Ferreira QueirozInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva 4, Switzerland.ORCID https://orcid.org/0000-0001-9567-1664
Jean-Robert IosetDrugs for Neglected Diseases Initiative (DNDi), 1202 Geneva, Switzerland.
Antonio GrondinGreen Mission Pierre Fabre, Institut de Recherche Pierre Fabre, 31562 Toulouse, France.ORCID https://orcid.org/0000-0002-2952-6271
Bruno DavidGreen Mission Pierre Fabre, Institut de Recherche Pierre Fabre, 31562 Toulouse, France.ORCID https://orcid.org/0000-0002-6222-9228
Jean-Luc WolfenderInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva 4, Switzerland.ORCID https://orcid.org/0000-0002-0125-952X
Pierre-Marie AllardInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva 4, Switzerland.ORCID https://orcid.org/0000-0003-3389-2191

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ENPKG framework organizes large heterogeneous metabolomics data sets as a knowledge graph, offering exciting opportunities for drug discovery and chemodiversity characterization.

Identifiers

PMID38559298
PMCPMC10979503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.