Evidence map›Paper›PMID 38559263›Full record

ArticlebioRxiv : the preprint server for biology2025

Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease.

Duy-Thanh Vu, Duy-Cat Can, Christelle Schneuwly Diaz, Julien S Bodelet, Guillaume E Blanc, Huy Phan, Gilles Allali, Viet-Dung Nguyen, Hengyi Cao, Xingru He and 12 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 9 institutions in 7 countries.

Duy-Thanh VuPlatform of Bioinformatics, Lausanne University Hospital, Lausanne, Switzerland.
Duy-Cat CanPlatform of Bioinformatics, Lausanne University Hospital, Lausanne, Switzerland.
Christelle Schneuwly DiazPlatform of Bioinformatics, Lausanne University Hospital, Lausanne, Switzerland.
Julien S BodeletPlatform of Bioinformatics, Lausanne University Hospital, Lausanne, Switzerland.
Guillaume E BlancPlatform of Bioinformatics, Lausanne University Hospital, Lausanne, Switzerland.
Huy PhanDepartment of Electrical Engineering, KU Leuven, Leuven, Belgium.
Gilles AllaliCentre Leenaards de la mémoire, CHUV, Lausanne, Switzerland.
Viet-Dung NguyenÉcole Nationale Supérieure de Techniques Avancées de Bretagne, Bretagne, France.
Hengyi CaoFeinstein Institutes for Medical Research, Manhasset, NY, USA.
Xingru HeSchool of Public Health, He University, Shengyang, China.
Yannick MüllerPlatform of Bioinformatics, Lausanne University Hospital, Lausanne, Switzerland.
Bangdong ZhiInnovation and Healthcare Group, University of Bristol, Bristol, UK.
Haochang ShouDepartment of Biostatistics, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-3043-047X
Haoyu ZhangDivision of Cancer Epidemiology and Genetics, NIH, Bethesda, MD, USA.
Wei HeSchool of Public Health, He University, Shengyang, China.
Xiaojun WangInnovation and Healthcare Group, University of Bristol, Bristol, UK.
Marcus MunafòSchool of Psychological Science, University of Bristol, Bristol, UK.ORCID 0000-0002-4049-993X
Guy NagelsDepartment of Neurology, Universitair Ziekenhuis Brussel, Jette, Belgium.
Philippe RyvlinDépartement des neurosciences cliniques, CHUV, Lausanne, Switzerland.ORCID 0000-0001-7775-6576
Nguyen Linh TrungVNU University of Engineering and Technology, Hanoi, Vietnam.
Giuseppe PantaleoFaculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Oliver Y ChénPlatform of Bioinformatics, Lausanne University Hospital, Lausanne, Switzerland.ORCID 0000-0002-5696-3127
SIB Swiss Institute of Bioinformatics · CHUniversity of Bristol · GBUniversity Hospital of Lausanne · CHFeinstein Institute for Medical Research · USNational Institutes of Health · USKU Leuven · BEUniversité de Bretagne Occidentale · FRUniversity of Oxford · GBVietnam National University, Hanoi · VN

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
WASHINGTON UNIVERSITY ALZHEIMERS DISEASE RESEARCH CENTERP50AG005681 · NIA · WASHINGTON UNIVERSITY · PI FAGAN, ANNE · 1985 to 2019
$52.1M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
MORPHOMETRY BIOMEDICAL INFORMATICS RESEARCH NETWORKU24RR021382 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2004 to 2008
$24.1M
STRUCTURE, FUNCTION AND COGNITION IN SCHIZOPHRENIAP50MH071616 · NIMH · WASHINGTON UNIVERSITY · PI BARCH, DEANNA · 2004 to 2008
$11.2M
Functional-anatomic exploration of cognitive controlR01AG021910 · NIA · WASHINGTON UNIVERSITY · PI BUCKNER, RANDY L · 2005 to 2009
$1.2M
NCRR NIH HHS U24 RR021382NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS P50 AG005681NIA NIH HHS R01 AG021910NIA NIH HHS U01 AG024904NIMH NIH HHS P50 MH071616
6 · The paper itself

Abstract

Alzheimer's Disease (AD) is the leading cause of dementia, affecting brain structure, function, cognition, and behaviour. While previous studies have linked brain regions to univariate outcomes (

Identifiers

PMID38559263
PMCPMC10979899
OpenAlexW4392815750

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.