Evidence map›Paper›PMID 38559256›Full record

ArticlebioRxiv : the preprint server for biology2024

YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks.

Ning Tsao, Jennifer Olabode, Rebecca Rodell, Hua Sun, Joshua R Brickner, Miaw-Sheue Tsai, Elizabeth A Pollina, Chun-Kan Chen, Nima Mosammaparast

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ning Tsao
Jennifer Olabode
Rebecca Rodell
Hua Sun
Joshua R Brickner
Miaw-Sheue Tsai
Elizabeth A Pollina
Chun-Kan Chen
Nima Mosammaparast
Washington University in St. Louis · USLawrence Berkeley National Laboratory · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
MECHANISM AND REGULATION OF THE DNA ALKYLATION DAMAGE RESPONSER01CA193318 · NCI · WASHINGTON UNIVERSITY · PI MOSAMMAPARAST, NIMA · 2015 to 2024
$3.6M
A SIGNALING PATHWAY SPECIFIC FOR ALKYLATION DAMAGER01CA227001 · NCI · WASHINGTON UNIVERSITY · PI MOSAMMAPARAST, NIMA · 2018 to 2022
$1.8M
An RNA-Dependent Innate Immune Response Pathway to Base-Damaging ChemotherapeuticsR01CA282733 · NCI · WASHINGTON UNIVERSITY · PI Nima Mosammaparast · 2024 to 2026
$1.5M
NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA193318NCI NIH HHS R01 CA227001NCI NIH HHS R01 CA282733
6 · The paper itself

Abstract

Certain environmental toxins are nucleic acid damaging agents, as are many chemotherapeutics used for cancer therapy. These agents induce various adducts in DNA as well as RNA. Indeed, most of the nucleic acid adducts (>90%) formed due to these chemicals, such as alkylating agents, occur in RNA

Identifiers

PMID38559256
PMCPMC10979943
OpenAlexW4392968983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.