Evidence map›Paper›PMID 38559194›Full record

ArticlebioRxiv : the preprint server for biology2024

Escape from X inactivation is directly modulated by levels of Xist non-coding RNA.

Antonia Hauth, Jasper Panten, Emma Kneuss, Christel Picard, Nicolas Servant, Isabell Rall, Yuvia A Pérez-Rico, Lena Clerquin, Nila Servaas, Laura Villacorta and 8 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 12 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 5 countries.

Antonia HauthEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.ORCID 0000-0002-6165-4468
Jasper PantenDivision of Regulatory Genomics and Cancer Evolution, German Cancer Research Centre (DKFZ), 69120, Heidelberg, Germany.ORCID 0000-0003-4697-7311
Emma KneussEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.ORCID 0000-0003-0662-8539
Christel PicardEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.
Nicolas ServantBioinformatics and Computational Systems Biology of Cancer, INSERM U900, Paris 75005, France.ORCID 0000-0003-1678-7410
Isabell RallEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.ORCID 0000-0001-5911-4609
Yuvia A Pérez-RicoEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.ORCID 0000-0001-8436-0748
Lena ClerquinEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.
Nila ServaasEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, 69117 Heidelberg, Germany.ORCID 0000-0002-9825-7554
Laura VillacortaEuropean Molecular Biology Laboratory, Genomics Core Facility, 69117 Heidelberg, Germany.ORCID 0000-0002-9509-8594
Ferris JungEuropean Molecular Biology Laboratory, Genomics Core Facility, 69117 Heidelberg, Germany.ORCID 0000-0002-5534-7832
Christy LuongCenter for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-2841-9930
Howard Y ChangCenter for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA.
Judith B ZauggEuropean Molecular Biology Laboratory, Structural and Computational Biology Unit, 69117 Heidelberg, Germany.ORCID 0000-0001-8324-4040
Oliver StegleEuropean Molecular Biology Laboratory, Genome Biology Unit, 69117 Heidelberg, Germany.ORCID 0000-0002-8818-7193
Duncan T OdomDivision of Regulatory Genomics and Cancer Evolution, German Cancer Research Centre (DKFZ), 69120, Heidelberg, Germany.ORCID 0000-0001-6201-5599
Agnese LodaEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.ORCID 0000-0001-8109-128X
Edith HeardEuropean Molecular Biology Laboratory, Directors' Research, 69117 Heidelberg, Germany.ORCID 0000-0001-8052-7117
European Molecular Biology Laboratory · DEGerman Cancer Research Center · DEEuropean Molecular Biology Organization · DECentre National de la Recherche Scientifique · FRCollège de France · FREuropean Molecular Biology Laboratory · DEHoward Hughes Medical Institute · USInserm · FRRoche (Switzerland) · CHStanford University · US

Funding

Center for Personal Dynamic RegulomesRM1HG007735 · NHGRI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2019 to 2023
$13.8M
NHGRI NIH HHS RM1 HG007735Wellcome Trust
6 · The paper itself

Abstract

In placental females, one copy of the two X chromosomes is largely silenced during a narrow developmental time window, in a process mediated by the non-coding RNA Xist

Identifiers

PMID38559194
PMCPMC10979913
OpenAlexW4392200703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.