Evidence map›Paper›PMID 38559169›Full record

ArticlebioRxiv : the preprint server for biology2024

Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking.

Zahra Z Farahbakhsh, Katherine M Holleran, Jonathon P Sens, Steve C Fordahl, Madelyn I Mauterer, Alberto J López, Verginia C Cuzon Carlson, Drew D Kiraly, Kathleen A Grant, Sara R Jones and 1 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Zahra Z FarahbakhshORCID 0000-0002-0909-7377
Katherine M HolleranORCID 0000-0002-2931-8157
Jonathon P Sens
Steve C Fordahl
Madelyn I Mauterer
Alberto J López
Verginia C Cuzon Carlson
Kathleen A Grant
Sara R Jones
Wake Forest University · USVanderbilt University · USOregon National Primate Research Center · USUniversity of North Carolina at Greensboro · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Translational measures of risk for excessive alcohol consumptionP60AA010760 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI TAMARA J. PHILLIPS · 2006 to 2026
$34.5M
Targeting the host metabolome to reverse drug-induced epigenetic changesDP1DA051551 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KIRALY, DREW · 2020 to 2024
$2.8M
Mesocortical neuromodulation in punishment-resistant alcohol drinkingR01AA030115 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.1M
8/8: INIA Stress and Chronic Alcohol Interactions: Cross-species plasticity signatures of alcohol and stressU01AA029971 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.0M
Defining the role of cortical circuit dynamics in learning and addictionR00DA045103 · NIDA · VANDERBILT UNIVERSITY · PI SICILIANO, CODY · 2020 to 2022
$764k
Role of the kappa opioid receptor system in learning and substance use disordersF31DA056196 · NIDA · VANDERBILT UNIVERSITY · PI FARAHBAKHSH, ZAHRA · 2023 to 2024
$56k
NIAAA NIH HHS P60 AA010760NIAAA NIH HHS R01 AA030115NIAAA NIH HHS U01 AA029971NIDA NIH HHS DP1 DA051551NIDA NIH HHS F31 DA056196NIDA NIH HHS R00 DA045103NIH HHS P51 OD011092
6 · The paper itself

Abstract

Alcohol use disorder is marked by disrupted behavioral and emotional states which persist into abstinence. The enduring synaptic alterations that remain despite the absence of alcohol are of interest for interventions to prevent relapse. Here, 28 male rhesus macaques underwent over 20 months of alcohol drinking interspersed with three 30-day forced abstinence periods. After the last abstinence period, we paired direct sub-second dopamine monitoring via

Identifiers

PMID38559169
PMCPMC10979957
OpenAlexW4392895875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.