Evidence map›Paper›PMID 38559104›Full record

ArticlebioRxiv : the preprint server for biology2024

An octopamine-specific GRAB sensor reveals a monoamine relay circuitry that boosts aversive learning.

Mingyue Lv, Ruyi Cai, Renzimo Zhang, Xiju Xia, Xuelin Li, Yipan Wang, Huan Wang, Jianzhi Zeng, Yifei Xue, Lanqun Mao and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Mingyue LvState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Ruyi CaiState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Renzimo ZhangState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Xiju XiaState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Xuelin LiState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Yipan WangState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Huan WangState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Jianzhi ZengState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Yifei XueCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Lanqun MaoCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Yulong LiState Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China.
Peking University · CNBeijing Normal University · CN

Funding

Novel fluorescent sensors for imaging neuromodulationU01NS113358 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DAN, YANG, LI, YULONG · 2019 to 2022
$4.3M
Optimization of GPCR-based fluorescent sensors for large-scale multiplexed in vivo imaging of neuromodulationU01NS120824 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIRES, SAMUEL ANDREW, LI, YULONG · 2021 to 2024
$3.6M
NINDS NIH HHS U01 NS113358NINDS NIH HHS U01 NS120824
6 · The paper itself

Abstract

Octopamine (OA), analogous to norepinephrine in vertebrates, is an essential monoamine neurotransmitter in invertebrates that plays a significant role in various biological functions, including olfactory associative learning. However, the spatial and temporal dynamics of OA

Indexed as

dopamineGRAB sensorlearning and memoryoctopamine

Identifiers

PMID38559104
PMCPMC10979849
OpenAlexW4392778851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.