Evidence map›Paper›PMID 38559101›Full record

ArticlebioRxiv : the preprint server for biology2024

PET Imaging of the Serotonin 1A Receptor in Major Depressive Disorder: Hierarchical Multivariate Analysis of [

Granville J Matheson, Francesca Zanderigo, Jeffrey M Miller, Elizabeth A Bartlett, J John Mann, R Todd Ogden

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Granville J MathesonDepartment of Psychiatry, Columbia University, New York, 10032 NY, USA.ORCID 0000-0002-5646-4547
Francesca ZanderigoDepartment of Psychiatry, Columbia University, New York, 10032 NY, USA.ORCID 0000-0001-6510-0676
Jeffrey M MillerDepartment of Psychiatry, Columbia University, New York, 10032 NY, USA.
Elizabeth A BartlettDepartment of Psychiatry, Columbia University, New York, 10032 NY, USA.
J John MannDepartment of Psychiatry, Columbia University, New York, 10032 NY, USA.ORCID 0000-0002-0265-6586
R Todd OgdenDepartment of Psychiatry, Columbia University, New York, 10032 NY, USA.ORCID 0009-0008-0005-446X
New York State Psychiatric InstituteStockholm County Council · SE

Funding

Suicidal Behavior: Aggression Subtypes, Childhood Adversity and Stress ResponseP50MH090964 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANN, JOSEPH JOHN · 2013 to 2022
$23.6M
Advanced Modeling Techniques for Brain Imaging Data with PETR01EB024526 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OGDEN, TODD · 2017 to 2020
$1.5M
NIBIB NIH HHS R01 EB024526NIMH NIH HHS P50 MH090964
6 · The paper itself

Abstract

The serotonin 1A receptor has been linked to both the pathophysiology of major depressive disorder (MDD) and the antidepressant action of serotonin reuptake inhibitors. Most PET studies of the serotonin 1A receptor in MDD used the receptor antagonist radioligand, [carbonyl-

Identifiers

PMID38559101
PMCPMC10980040
OpenAlexW4392678538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.